Head-to-head · WeighScore
Enhance MD vs Southern Vitality and Weight Loss
The verdict
Enhance MD takes it — 84.8/100 to 65.2/100.
Enhance MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.
We may earn a commission through these links, at no extra cost to you. Commercial relationships affect placement, but never the WeighScore or our editorial findings. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Enhance MD | Southern Vitality and Weight Loss |
|---|---|---|
| WeighScore | 84.8/100 | 65.2/100 |
| Grade | B | C |
| Site position | #5 | #252 |
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | $199/mo (compounded) |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | $299/mo (compounded) |
| Coverage | Not publicly listed | 1 state |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Site position #5 · B
Strengths
- Transparent tiered pricing across sema, tirz, microdose, and combo
- Dose-flat — the price does not step up as you titrate
- Six-month lab testing plus provider-led care
- NAD+ longevity adjacency available
Where it loses points
- Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
- No oral or sublingual route
- States served are not published
- Higher entry price than the cheapest compounded programs
Site position #252 · C
Strengths
- Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
- Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
- Free telehealth consult and free shipping; no membership or hidden fees
- Bi-weekly check-ins; operating since 2012
- Flexible monthly financing available at checkout
Where it loses points
- This is one physical clinic in Valdosta, Georgia, not a national telehealth service — nothing here is available to a reader outside Georgia
- The advertised 'as low as $99/month' is a semaglutide three-month starter pack ($299 paid up front), not a tirzepatide rate and not a monthly one
- Month-to-month rates are $199 semaglutide and $299 tirzepatide
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
Featured provider
Enhance MD
Enhance MD scores 84.8/100 (B). A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.
Commercial relationships affect this placement. The score comparison above is separate.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.