Head-to-head · WeighScore
Enhance MD vs RxPepsDirect
The verdict
Enhance MD takes it — 84.8/100 to 68.7/100.
Enhance MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Enhance MD | RxPepsDirect |
|---|---|---|
| WeighScore | 84.8/100 | 68.7/100 |
| Grade | B | C |
| Site position | #5 | #158 |
| Semaglutide | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay | $79 starting order (compounded semaglutide/B12, $25 vial + $39 visit + $15 shipping) |
| Tirzepatide | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay | $99 starting order (compounded tirzepatide/B12, $45 vial + $39 visit + $15 shipping) |
| Coverage | Not publicly listed | 28 states plus DC |
| Brand-name access | Not confirmed | Not confirmed |
| Oral / sublingual | Not confirmed | Not confirmed |
Site position #5 · B
Strengths
- Transparent tiered pricing across sema, tirz, microdose, and combo
- Dose-flat — the price does not step up as you titrate
- Six-month lab testing plus provider-led care
- NAD+ longevity adjacency available
Where it loses points
- Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
- No oral or sublingual route
- States served are not published
- Higher entry price than the cheapest compounded programs
Site position #158 · C
Strengths
- Full semaglutide/B12 and tirzepatide/B12 vial price ladders are public
- No membership; automatic refills are optional and can be disabled in the dashboard
- Names Optimal Balance Pharmacy and publishes sample sterility and endotoxin reports
Where it loses points
- Starting-order totals are not guaranteed ongoing monthly treatment prices
- The $39 visit fee recurs per order and is nonrefundable once clinical review begins, even if denied
- Pharmacy payments have separate refund terms
- Compounded protocols and testing reports do not establish FDA approval or equivalence to branded trial results
Featured provider
Enhance MD
Enhance MD scores 84.8/100 (B). A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.
Commercial relationships affect this placement. The score comparison above is separate.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.