Head-to-head · WeighScore
1st Optimal vs Trimi
The verdict
Trimi takes it — 86.4/100 to 61.6/100.
Trimi grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Bottom-quartile pricing on both molecules under one flat membership, shipped free nationwide — a strong-value pick sitting just behind the top tier.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | Trimi |
|---|---|---|
| WeighScore | 61.6/100 | 86.4/100 |
| Grade | C | B |
| Scorecard rank | #288 | #7 |
| Semaglutide | Not disclosed | $129/mo |
| Tirzepatide | Not disclosed | $199/mo |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #288 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #7 · B
Strengths
- Low flat pricing on both semaglutide and tirzepatide
- Both molecules on a single membership
- Free shipping to all 50 states
- Fast dispatch once the prescriber signs off
Where it loses points
- Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
- Injection only — no oral or sublingual route
- Dispensing pharmacy not publicly named
- Shorter public track record than the incumbents
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.