1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Compounded only
Line 1st Optimal up against its closest alternatives. Because 1st Optimal dispenses compounded medication, it’s worth understanding whether compounded semaglutide is legit and safe.
Factor breakdown
Each of the six graded dimensions. See the methodology.
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Bottom line — Grade C
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Ranked #315 of 544 on this scorecard. See our top-scoring pick, CoreAge Rx (#1), for comparison.
Closest here
The rankings grading nearest 1st Optimal — the realistic shortlist.
DadVantage Men's Health is a Florida concierge men's clinic offering GLP-1 weight loss alongside testosterone and hormone optimization, peptide therapy, sexual health, and PRP.
Unique Physique is a hybrid in-office and telehealth weight-loss clinic in Baton Rouge, Louisiana, with medical oversight from Reena John, DO.
Ten-vertical telehealth marketplace selling compounded GLP-1 tiers alongside HRT, ED, nootropics and peptides, running on the Bask Health platform.
Fitstry is the GLP-1 weight-loss program of Weightstry, LLC, a LegitScript-certified, cash-pay telehealth practice focused on women 40+.
Bioverse (GoBioverse) offers compounded semaglutide and tirzepatide plus brand-name Ozempic, Wegovy, and Mounjaro.
Genesis Health is a telehealth platform offering compounded semaglutide and tirzepatide injections alongside brand-name Wegovy, Ozempic, and Zepbound.
The 18 rankings nearest this one
- #319 HumeCare+58.6
- #323 Signos61.4
- #324 Tryozi61.4
- #325 WePeptideRx61.4
- #326 BloomWell Rx61.3
- #327 Call-On-Doc61.3
- #328 MyStart Health61.3
- #329 Alinwell61.2
- #330 HelloWellness61.2
- #331 LunaRx61.2
- #332 Trinity Meds61.2
- #333 Clinic Secret61.1
- #334 TeleHealth Weight Solutions61.1
- #335 Invyncible61
- #336 Liberty61
- #337 Luvo Health61
- #338 Medsol RX61
- #339 Ascend Vitality60.9
Pricing/verification reflect 1st Optimal's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on 1st Optimal's site. Not medical advice; see our disclosure.