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Graded #291

1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.

Visit 1st Optimal ↗We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Semaglutide
Not disclosed
Tirzepatide
Not disclosed
Coverage
Coverage not published
Brand-name
Compounded only

Line 1st Optimal up against its closest alternatives. Because 1st Optimal dispenses compounded medication, it’s worth understanding whether compounded semaglutide is legit and safe.

Factor breakdown

Each of the six graded dimensions. See the methodology.

Cost value45/100
Dose & formulation51/100
Clinical oversight77/100
Labs & monitoring97/100
Fulfillment60/100
Contract terms37/100

Strengths

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Where it loses points

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Bottom line — Grade C

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Ranked #291 of 499 on this scorecard. See our top-scoring pick, CoreAge Rx (#1), for comparison.

Visit 1st Optimal ↗

Closest on the board

The boards grading nearest 1st Optimal — the realistic shortlist.

CVS MinuteClinic#290

CVS MinuteClinic® Weight Loss Program offers FDA-approved brand-name GLP-1 medications (semaglutide, tirzepatide, liraglutide/Saxenda) at in-clinic or virtual visits — no compounded products.

DadVantage Men's Health#292

DadVantage Men's Health is a Florida concierge men's clinic offering GLP-1 weight loss alongside testosterone and hormone optimization, peptide therapy, sexual health, and PRP.

Youth & Soul#293

Ten-vertical telehealth marketplace selling compounded GLP-1 tiers alongside HRT, ED, nootropics and peptides, running on the Bask Health platform.

Signos#294

Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with…

Tryozi#295

Florida telehealth selling compounded GLP-1 injections at a flat price that does not rise with dose, naming all four of its 503A compounding pharmacies.

Unique Physique#296

Unique Physique is a hybrid in-office and telehealth weight-loss clinic in Baton Rouge, Louisiana, with medical oversight from Reena John, DO.

The 19 boards nearest this one

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Pricing/verification reflect 1st Optimal's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on 1st Optimal's site. Not medical advice; see our disclosure.

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