1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Not confirmed
Line 1st Optimal up against its closest alternatives. If you are considering a compounded option, read about whether compounded semaglutide is legit and safe.
Factor breakdown
These are recorded editorial marks, not a measure of clinical outcomes. Current prices and policies may differ from those used in the marks. See the methodology.
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
What to consider
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Bottom line — Grade C
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Site position #324 of 541. Commercial relationships affect placement, not the score. See our featured provider, CoreAge Rx (#1), for comparison.
Closest here
The rankings grading nearest 1st Optimal — the realistic shortlist.
DadVantage Men's Health is a Florida concierge men's clinic offering GLP-1 weight loss alongside testosterone and hormone optimization, peptide therapy, sexual health, and PRP.
Unique Physique is a hybrid in-office and telehealth weight-loss clinic in Baton Rouge, Louisiana, with medical oversight from Reena John, DO.
Ten-vertical telehealth marketplace selling compounded GLP-1 tiers alongside HRT, ED, nootropics and peptides, running on the Bask Health platform.
Fitstry is the GLP-1 weight-loss program of Weightstry, LLC, a LegitScript-certified, cash-pay telehealth practice focused on women 40+.
Bioverse (GoBioverse) offers compounded semaglutide and tirzepatide plus brand-name Ozempic, Wegovy, and Mounjaro.
Genesis Health is a telehealth platform offering compounded semaglutide and tirzepatide injections alongside brand-name Wegovy, Ozempic, and Zepbound.
The 18 rankings nearest this one
- #328 HumeCare+58.6
- #332 Signos61.4
- #333 Tryozi61.4
- #334 WePeptideRx61.4
- #335 BloomWell Rx61.3
- #336 Call-On-Doc61.3
- #337 MyStart Health61.3
- #338 Alinwell61.2
- #339 HelloWellness61.2
- #340 LunaRx61.2
- #341 Trinity Meds61.2
- #342 Willow58.2
- #343 Clinic Secret61.1
- #344 TeleHealth Weight Solutions61.1
- #345 Liberty61
- #346 Luvo Health61
- #347 Ascend Vitality60.9
- #348 Bliv60.9
Pricing/verification reflect 1st Optimal's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on 1st Optimal's site. Not medical advice; see our disclosure.