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Graded #323

Signos

Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with real-time glucose data and coaching so users understand and sustain their weight loss.

Visit Signos ↗We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Semaglutide
$199/mo (6-month plan, compounded)
Tirzepatide
$199/mo (starting dose, compounded)
Coverage
Coverage not published
Brand-name
Compounded only

Weigh Signos against the full graded field on the best semaglutide providers scorecard, or line it up against its closest alternatives. Because Signos dispenses compounded medication, it’s worth understanding whether compounded semaglutide is legit and safe.

Factor breakdown

Each of the six graded dimensions. See the methodology.

Cost value44/100
Dose & formulation64/100
Clinical oversight84/100
Labs & monitoring71/100
Fulfillment71/100
Contract terms20/100

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Bottom line — Grade C

Best for: Shoppers who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.

Ranked #323 of 544 on this scorecard. See our top-scoring pick, CoreAge Rx (#1), for comparison.

Visit Signos ↗

Closest here

The rankings grading nearest Signos — the realistic shortlist.

Genesis Health#322

Genesis Health is a telehealth platform offering compounded semaglutide and tirzepatide injections alongside brand-name Wegovy, Ozempic, and Zepbound.

Tryozi#324

Florida telehealth selling compounded GLP-1 injections at a flat price that does not rise with dose, naming all four of its 503A compounding pharmacies.

WePeptideRx#325

WePeptideRx is a provider-guided telehealth platform offering compounded semaglutide and tirzepatide alongside a deep menu of peptide, hormone, hair, and sexual-wellness programs.

BloomWell Rx#326

BloomWell Rx is a 100% online telehealth service offering personalized compounded GLP-1 weight loss — semaglutide (from $199/mo) and tirzepatide/GLP-1+GIP (from $249/mo) — after a free visit, plus wellness options like NAD+, sermorelin, and glutathione.

Call-On-Doc#327

Call-On-Doc is a large multi-condition online telehealth service (2M+ patients, 800k+ five-star reviews) offering a GLP-1 weight-loss program.

MyStart Health#328

MyStart Health offers all-inclusive compounded semaglutide and tirzepatide at $299/month with a price-lock guarantee, same-day physician consultations, and 24/7 care team access.

The 19 rankings nearest this one

View full scorecard rankings →

Pricing/verification reflect Signos's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on Signos's site. Not medical advice; see our disclosure.

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