Head-to-head · WeighScore
Human+ vs Signos
The verdict
Signos takes it — 61.4/100 to 59.8/100, but only just.
Signos grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with… Human+ is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Human+ | Signos |
|---|---|---|
| WeighScore | 59.8/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #334 | #295 |
| Semaglutide | Not disclosed | $199/mo (6-month plan, compounded) |
| Tirzepatide | Not disclosed | $199/mo (starting dose, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #334 · C
Strengths
- Cost-transparent model: a flat monthly membership with prescriptions billed at pharmacy-wholesale cost instead of marked up
- Available via telehealth in all 50 states
- Filled by US 503A compounding pharmacies and reviewed by board-certified US-licensed clinicians
- Fast, fully online 5-minute intake with provider review often within hours; discreet plain packaging
- Covers weight loss plus hair, sexual wellness, mental health, and labs under one membership
Where it loses points
- Specific GLP-1 medications and pricing are not published — you only see them after starting the intake
- Compounded medications are not FDA-approved — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- LegitScript certification is shown only as a self-hosted badge; no verifiable LegitScript seal was found
- Minimal public-facing site and a flat membership fee on top of the medication cost
Graded #295 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.