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Head-to-head · WeighScore

Enhance MD vs System Labs

Enhance MD
Site position #5

Higher grade

vs+16.4
System Labs
Site position #102

Lower grade

The verdict

Enhance MD takes it — 84.8/100 to 68.4/100.

Enhance MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.

We may earn a commission through these links, at no extra cost to you. Commercial relationships affect placement, but never the WeighScore or our editorial findings. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSystem Labs +4
82
86
Dose & formulationEnhance MD +30
82
52
Clinical oversightEnhance MD +16
88
72
Labs & monitoringEnhance MD +50
90
40
FulfillmentEnhance MD +6
84
78
Contract termsEven
84
84
Enhance MD · left barSystem Labs · right bar

The numbers

MetricEnhance MDSystem Labs
WeighScore84.8/10068.4/100
GradeBC
Site position#5#102
Semaglutide$249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepayNot offered
Tirzepatide$329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay$179/mo flat at every dose ($99 first month only, then $179)
CoverageNot publicly listedNot disclosed
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Enhance MD

Site position #5 · B

Strengths

  • Transparent tiered pricing across sema, tirz, microdose, and combo
  • Dose-flat — the price does not step up as you titrate
  • Six-month lab testing plus provider-led care
  • NAD+ longevity adjacency available

Where it loses points

  • Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
  • No oral or sublingual route
  • States served are not published
  • Higher entry price than the cheapest compounded programs
System Labs

Site position #102 · C

Strengths

  • A flat $179/mo month-to-month rate at every dose, stated in the company's own FAQ as "a flat $179/mo with no hidden fees" — there is no prepay rung to buy down to it, no membership fee and no per-visit charge on top
  • Three named physicians with checkable credentials sit on the medical board — Dr Marc Gruner (sports medicine, trained at Mayo Clinic), Dr Jonathan Hinds (board-certified emergency medicine, trained at Rutgers) and Dr Gregory Tennant (fellowship-trained orthopedic trauma surgeon, trained at Vanderbilt) — where most of this ranking names nobody at all
  • Free two-day temperature-controlled shipping with injection supplies included, automatic refills on your own schedule, and pause or cancel yourself from the dashboard
  • The lander carries its own bolded disclosure that the compounded product is not FDA-approved, rather than leaving a reader to work that out afterwards

Where it loses points

  • One molecule only — the product is a compounded GLP-1/GIP built on tirzepatide, and there is no semaglutide option at any price
  • The advertised "$99" is a first-month introductory rate, labeled "/first mo." on the page itself; from month two the bill is $179, so the first charge is not the standing cost
  • Weekly subcutaneous injection only — no oral or sublingual route, and no brand-name Zepbound or Mounjaro lane
  • The states served are published nowhere; one ranking physician is described as licensed in all 50, which is a fact about a clinician and not a statement of where the company can dispense
  • The dispensing pharmacy is identified only as "a certified U.S. pharmacy" — never a facility, never a city, never a 503A or 503B designation
  • No lab or monitoring program is published — nothing states whether baseline or follow-up bloodwork is required, included in the price, or billed on top of it
  • Compounded tirzepatide is not FDA-approved and is not a generic equivalent of Zepbound or Mounjaro
  • The testimonials are first-name-and-age only, and several of them praise the NAD+ and glutathione lines rather than the GLP-1 program, so they are no evidence about this product

Featured provider

Enhance MD

Enhance MD scores 84.8/100 (B). A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.

Commercial relationships affect this placement. The score comparison above is separate.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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