Head-to-head · WeighScore
EdgeRx vs Lyfe Rx
The verdict
EdgeRx takes it — 79/100 to 55.9/100.
EdgeRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A men's-only compounded GLP-1 program that names its pharmacy (Strive Pharmacy, 503A since 2018) and its Chief Medical Advisor — real transparency signals most compounders skip.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | EdgeRx | Lyfe Rx |
|---|---|---|
| WeighScore | 79/100 | 55.9/100 |
| Grade | C+ | C |
| Scorecard rank | #41 | #435 |
| Semaglutide | $229/mo | $225/mo (compounded) |
| Tirzepatide | $299/mo | $299/mo (compounded) |
| Coverage | 46 states (excludes Arkansas, Indiana, Minnesota, South Carolina) | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #41 · C+
Strengths
- Named compounding pharmacy — Strive Pharmacy, a 503A facility compounding since 2018 — a genuine transparency signal most compounders lack
- Named Chief Medical Advisor, Dr. John Starke, MD (ABEM board-certified)
- LegitScript certified, once-weekly injectable, free shipping, no separate physician fee
- Broad protocol menu beyond GLP-1 — MICC lipotropic, sermorelin/NAD+/glutathione, skin/hair, and sexual/hormonal health tiers
Where it loses points
- Men's-only positioning — not an option for women
- Dr. Starke does not personally prescribe; the actual prescribing pool is unnamed licensed physicians
- Third-party lab testing is claimed but no specific lab is named
- Excludes Arkansas, Indiana, Minnesota and South Carolina (46 states)
- Bloodwork cost is undisclosed on the Sexual & Hormonal Health tier
Graded #435 · C
FDAWarning letter issued to Lyfe Rx in September 2025. See the FDA warning-letter database.
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued Lyfe Rx a warning letter in September 2025; the letter is public in FDA's warning-letter database
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 509 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.