Head-to-head · WeighScore
DrBrainRx vs Signos
The verdict
DrBrainRx takes it — 70.8/100 to 61.4/100.
DrBrainRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. DrBrainRx is a neurologist-founded telehealth clinic led by Dr.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | DrBrainRx | Signos |
|---|---|---|
| WeighScore | 70.8/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #104 | #295 |
| Semaglutide | $199/mo (all doses, compounded) | $199/mo (6-month plan, compounded) |
| Tirzepatide | $299/mo (all doses, compounded) | $199/mo (starting dose, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #104 · C
Strengths
- Founded and overseen by Dr. Sara Siavoshi — triple board-certified in Neurology, Headache Medicine, and Obesity Medicine
- LegitScript certified with compounded medications from USP-certified 503B pharmacies
- Flat-rate pricing — same monthly cost for all dose levels (dose escalation does not raise price)
- 100% online with rapid approvals (~24-48 hours) and discreet shipping in 3–5 business days
- Side-effect support, dose adjustments, and injection guides included with provider care
Where it loses points
- Separate $25/month provider care fee (compounded track) on top of medication cost
- Compounded medications are not FDA-approved individual drugs
- Labs not required or included — no baseline bloodwork protocol disclosed
- States served not published; no explicit list available
- No dedicated coaching program beyond clinical dose management
Graded #295 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.