Head-to-head · WeighScore
Cost Plus Drugs vs ShedRx
The verdict
ShedRx takes it — 87/100 to 58.5/100.
ShedRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. The widest formulation spread on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound lane.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Cost Plus Drugs | ShedRx |
|---|---|---|
| WeighScore | 58.5/100 | 87/100 |
| Grade | C | B+ |
| Scorecard rank | #370 | #3 |
| Semaglutide | $279/mo (brand Ozempic) | $199/mo |
| Tirzepatide | Not disclosed | $299/mo |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #370 · C
Strengths
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Where it loses points
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Graded #3 · B+
Strengths
- Four GLP-1 routes — injection, liquid drops, lozenges and an oral daily pill
- Brand Zepbound and Wegovy available beside the compounded line
- Health coaching included with membership, plus a published 120-day weight-loss guarantee
Where it loses points
- The advertised "as low as $239" tirzepatide rate requires a twelve-month commitment — month-to-month is $299
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
- The dispensing compounding pharmacy is not publicly named
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.