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Head-to-head · WeighScore

CLYR Health vs Sesame Care

CLYR Health
Graded #302

Lower grade

vs+25.6
Sesame Care
Graded #2

Higher grade

The verdict

Sesame Care takes it — 87.8/100 to 62.2/100.

Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

We may earn a commission through these links, at no extra cost to you. Commercial relationships affect placement, but never the WeighScore or our editorial findings. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSesame Care +45
39
84
Dose & formulationSesame Care +4
88
92
Clinical oversightSesame Care +20
74
94
Labs & monitoringSesame Care +32
52
84
FulfillmentSesame Care +3
77
80
Contract termsSesame Care +55
37
92
CLYR Health · left barSesame Care · right bar

The numbers

MetricCLYR HealthSesame Care
WeighScore62.2/10087.8/100
GradeCB+
Scorecard rank#302#2
Semaglutide$169 per 28-day vial (starting dose, compounded; higher doses $199–229)Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year)
Tirzepatide$149 first month (starting dose, compounded; continuing doses $249–329/month)Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days
CoverageCoverage not publishedNationwide marketplace
Brand-name accessYesYes
Oral / sublingualYesYes
CLYR Health

Graded #302 · C

Strengths

  • Dose-specific prices and one- or two-month purchase totals are published before intake
  • Product pages include consultation, medication, syringes, and shipping in the price
  • Terms name MD Integrations and The Pharmacy Hub as partners
  • Brand-name and oral options are also listed in the weight-loss catalog

Where it loses points

  • Prices rise by dose; the tirzepatide starter offer is not a continuing flat rate
  • Product pages promise one-time billing but general terms still describe subscriptions and stricter refund rules
  • The semaglutide page contains conflicting cold-pack and room-temperature shipping descriptions
  • State eligibility depends on treatment and is checked during intake
Sesame Care

Graded #2 · B+

Strengths

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency
  • Oral routes available (Wegovy pill, Rybelsus)

Where it loses points

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Also worth a look

Another provider to compare: CoreAge Rx

CoreAge Rx scores 89.5/100 (B+). CoreAge Rx advertises flat dose pricing for compounded injections, with no membership fee; its consultation-fee and refund deadlines deserve a close read before paying.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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