Head-to-head · WeighScore
Calibrate Health vs Enhance MD
The verdict
Enhance MD takes it — 84.8/100 to 69.3/100.
Enhance MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A transparently tiered compounded program — semaglutide $212/mo (first month $112), tirzepatide $280, a $169 microdose, and a $322 combo — backed by six-month lab testing and provider care, with NAD+ on the side.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Calibrate Health | Enhance MD |
|---|---|---|
| WeighScore | 69.3/100 | 84.8/100 |
| Grade | C | B |
| Scorecard rank | #125 | #11 |
| Semaglutide | Not disclosed | $212/mo |
| Tirzepatide | Not disclosed | $280/mo |
| Coverage | All 50 states | Not publicly listed |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #125 · C
Strengths
- Year-long program with 1:1 video coaching, dietitian support, and behavior-change curriculum — a deeper clinical wrap than transactional telehealth
- $199/month program fee is competitive; medication co-pay can drop to ~$25/month with insurance and a manufacturer savings card
- Branded GLP-1s only (Wegovy, Ozempic, Zepbound, Foundayo) — no compounded products
- Insurance navigation team works to maximize coverage and reportedly accepts most major commercial plans
- Money-back guarantee tied to a 10% weight-loss outcome over the program year
Where it loses points
- Medication cost is on top of the $199/month fee; cash-pay patients face full manufacturer pricing
- Insurance navigation only helps if your plan actually covers branded GLP-1s for weight loss — many don't
- Meaningfully more expensive than compounded telehealth if your insurance denies coverage
- Distinct from 'Oxford's Medical Weight Loss (The Calibrate Clinic)' — don't confuse the two
- Initial 3-month commitment required ($597 total, billed as $199/mo) before it renews month-to-month — more lock-in than month-to-month rivals
Graded #11 · B
Strengths
- Transparent tiered pricing across sema, tirz, microdose, and combo
- Dose-flat — the price does not step up as you titrate
- Six-month lab testing plus provider-led care
- NAD+ longevity adjacency available
Where it loses points
- Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
- No oral or sublingual route
- States served are not published
- Higher entry price than the cheapest compounded programs
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.