Head-to-head · WeighScore
1st Optimal vs telos rx
The verdict
telos rx takes it — 85.4/100 to 61.6/100.
telos rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A LegitScript-certified, HIPAA telehealth with one of the deepest published catalogs on the board — compounded semaglutide and tirzepatide (oral and microdosed routes included) alongside PT-141, intranasal NAD+, and a long recovery/GH peptide bench — with compounded GLP-1 starting from $49/mo on an annual plan.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | 1st Optimal | telos rx |
|---|---|---|
| WeighScore | 61.6/100 | 85.4/100 |
| Grade | C | B |
| Scorecard rank | #288 | #9 |
| Semaglutide | Not disclosed | From $49/mo (annual) |
| Tirzepatide | Not disclosed | $99/mo (annual) |
| Coverage | Coverage not published | Not publicly listed |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
Graded #288 · C
Strengths
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Where it loses points
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Graded #9 · B
Strengths
- Deep published catalog — sema, tirz, PT-141, intranasal NAD+, recovery/GH peptides, GHK-Cu, Dihexa, HRT
- Needle-free and oral GLP-1 options, not injection-only
- LegitScript-certified and HIPAA, with US providers and pharmacies, HSA/FSA and free shipping
- Low GLP-1 entry — from $49/mo microdosed on an annual plan
Where it loses points
- Everything is compounded and not FDA-approved, including the peptides
- Pricing is opaque outside GLP-1 and the lowest rates require annual lock-in
- No named clinicians and thin third-party reviews
- Several research-grade peptides carry limited clinical evidence
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.