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Head-to-head · WeighScore

1st Optimal vs Calibrate Health

1st Optimal
Graded #291

Lower grade

vs+7.699999999999996
Calibrate Health
Graded #132

Higher grade

The verdict

Calibrate Health takes it — 69.3/100 to 61.6/100.

Calibrate Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Calibrate Health is a year-long metabolic-reset program pairing branded GLP-1 medication (Wegovy, Ozempic, Zepbound, or Foundayo) with 1:1 video coaching and dietitian support — a deeper clinical wrap than…

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Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
45
45
Dose & formulationCalibrate Health +2
51
53
Clinical oversightCalibrate Health +17
77
94
Labs & monitoring1st Optimal +9
97
88
FulfillmentCalibrate Health +32
60
92
Contract termsCalibrate Health +18
37
55
1st Optimal · left barCalibrate Health · right bar

The numbers

Metric1st OptimalCalibrate Health
WeighScore61.6/10069.3/100
GradeCC
Scorecard rank#291#132
SemaglutideNot disclosedNot disclosed
TirzepatideNot disclosedNot disclosed
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualYesInjection only
1st Optimal

Graded #291 · C

Strengths

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Where it loses points

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation
Calibrate Health

Graded #132 · C

Strengths

  • Year-long program with 1:1 video coaching, dietitian support, and behavior-change curriculum — a deeper clinical wrap than transactional telehealth
  • $199/month program fee is competitive; medication co-pay can drop to ~$25/month with insurance and a manufacturer savings card
  • Branded GLP-1s only (Wegovy, Ozempic, Zepbound, Foundayo) — no compounded products
  • Insurance navigation team works to maximize coverage and reportedly accepts most major commercial plans
  • Money-back guarantee tied to a 10% weight-loss outcome over the program year

Where it loses points

  • Medication cost is on top of the $199/month fee; cash-pay patients face full manufacturer pricing
  • Insurance navigation only helps if your plan actually covers branded GLP-1s for weight loss — many don't
  • Meaningfully more expensive than compounded telehealth if your insurance denies coverage
  • Distinct from 'Oxford's Medical Weight Loss (The Calibrate Clinic)' — don't confuse the two
  • Initial 3-month commitment required ($597 total, billed as $199/mo) before it renews month-to-month — more lock-in than month-to-month rivals

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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