Head-to-head · WeighScore
Signos vs Zera Health
The verdict
Zera Health takes it — 74.8/100 to 61.4/100.
Zera Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Zera Health is a telehealth platform for compounded GLP-1 weight loss — semaglutide from $149/mo, tirzepatide from $199/mo, plus oral and low-dose microdose options — prescribed by licensed physicians in…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Signos | Zera Health |
|---|---|---|
| WeighScore | 61.4/100 | 74.8/100 |
| Grade | C | C |
| Scorecard rank | #293 | #61 |
| Semaglutide | $199/mo (6-month plan, compounded) | $149/mo (compounded) |
| Tirzepatide | $199/mo (starting dose, compounded) | $199/mo (compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Graded #61 · C
Strengths
- Compounded semaglutide from $149/mo and tirzepatide from $199/mo, plus a $129/mo microdose option
- Flat pricing — the same monthly cost at every dose as you titrate up
- All-inclusive: medication, unlimited 24/7 provider messaging, and free shipping bundled in
- Names its compounding pharmacy — Strive Pharmacy (licensed 503A)
- Available in all 50 states with same-day approvals
Where it loses points
- Operates as a technology platform, not the medical provider itself
- Compounded GLP-1s are not FDA-approved (the site discloses this honestly)
- Aggressive marketing results claims (e.g. '18% average', '93% kept it off') with 'results not typical' disclaimers
- Legal entity name not published (footer shows only 'Zera Health')
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.