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Head-to-head · WeighScore

Signos vs Zappy Health

Signos
Graded #295

Lower grade

vs+4.800000000000004
Zappy Health
Graded #201

Higher grade

The verdict

Zappy Health takes it — 66.2/100 to 61.4/100.

Zappy Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Zappy Health is a telehealth weight-loss platform offering both compounded and brand-name GLP-1: compounded semaglutide from $159/month and tirzepatide from $299/month, plus brand Wegovy and Zepbound.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueZappy Health +22
44
66
Dose & formulationZappy Health +13
64
77
Clinical oversightSignos +17
84
67
Labs & monitoringSignos +20
71
51
FulfillmentSignos +1
71
70
Contract termsZappy Health +41
20
61
Signos · left barZappy Health · right bar

The numbers

MetricSignosZappy Health
WeighScore61.4/10066.2/100
GradeCC
Scorecard rank#295#201
Semaglutide$199/mo (6-month plan, compounded)$159/mo (compounded)
Tirzepatide$199/mo (starting dose, compounded)$299/mo (compounded)
CoverageCoverage not published42 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
Signos

Graded #295 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page
Zappy Health

Graded #201 · C

Strengths

  • Both compounded GLP-1 and brand-name Wegovy/Zepbound available
  • Flat pricing that doesn't increase as your dose goes up
  • Cheaper on longer subscriptions — compounded semaglutide from $159/month
  • Online visit with a licensed clinician; no insurance required

Where it loses points

  • Third-party reports of an order arriving with an unlicensed-pharmacy label
  • Not available in 8 states (HI, AL, AR, CA, KS, MI, MN, MS)
  • Operating legal entity isn't clearly disclosed on the site
  • Lowest prices require a 9-month commitment

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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