Head-to-head · WeighScore
Signos vs WePeptideRx
The verdict
Too close to call — both grade 61.4/100 (C).
Signos and WePeptideRx land on the same WeighScore, so neither clears the other on our six graded dimensions. Signos sits one line higher on the board (#294 vs #297) on the underlying tiebreak, but it's a genuine coin-flip — pick on the factors and prices that matter most to you below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Signos | WePeptideRx |
|---|---|---|
| WeighScore | 61.4/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #294 | #297 |
| Semaglutide | $199/mo (6-month plan, compounded) | $249/mo (compounded) |
| Tirzepatide | $199/mo (starting dose, compounded) | $249/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #294 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Graded #297 · C
Strengths
- Pre-mixed ready-to-inject delivery skips the vial reconstitution and sharps hassle of most compounded providers
- Microdose protocols (0.05–0.25 mg sema, 0.5–2.5 mg tirz) suit ultra-low-dose maintenance patients — uncommon in DTC
- 12+ programs under one platform — GLP-1 plus longevity, sexual wellness, and hair
- Physical Boca Raton address, phone, and business hours listed
- LegitScript Certified and publishes the FDA disclaimer
Where it loses points
- Pharmacy partner not named
- 48-state claim, but the specific state list isn't shown on the homepage
- Medical director not named on the homepage
- Telemedicine is outsourced to a third-party provider network rather than in-house staff
- Corporate legal entity and arbitration venue not disclosed
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.