Head-to-head · WeighScore
Signos vs Velvet Rx
The verdict
Signos takes it — 61.4/100 to 58.1/100.
Signos grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Signos | Velvet Rx |
|---|---|---|
| WeighScore | 61.4/100 | 58.1/100 |
| Grade | C | C |
| Scorecard rank | #293 | #381 |
| Semaglutide | $199/mo (6-month plan, compounded) | $299/mo (compounded) |
| Tirzepatide | $199/mo (starting dose, compounded) | $359/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Graded #381 · C
Strengths
- Public pricing across 3 SKUs (semaglutide $299, tirzepatide $359, oral GLP-1 $349) — uncommon in compounded telehealth
- First-month promo pricing shown upfront ($139 sema / $199 tirz / $189 oral)
- Single monthly price includes consult, prescription, 4 weeks of medication, and free 1–2 day shipping
- FSA/HSA eligible
- Three options under one roof: injectable sema, injectable tirz, and an oral GLP-1
Where it loses points
- Oral GLP-1 SKU doesn't name the specific drug — a real gap given Rybelsus, Foundayo, and compounded oral semaglutide differ clinically
- No LegitScript or NABP .pharmacy seal displayed
- No legal entity name disclosed
- No physical address disclosed
- Compounding pharmacy partner not named
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.