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Head-to-head · WeighScore

Signos vs Unique Physique

Signos
Graded #294

Level

vs
Unique Physique
Graded #296

Level

The verdict

Too close to call — both grade 61.4/100 (C).

Signos and Unique Physique land on the same WeighScore, so neither clears the other on our six graded dimensions. Signos sits one line higher on the board (#294 vs #296) on the underlying tiebreak, but it's a genuine coin-flip — pick on the factors and prices that matter most to you below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueUnique Physique +33
44
77
Dose & formulationSignos +3
64
61
Clinical oversightSignos +22
84
62
Labs & monitoringSignos +21
71
50
FulfillmentSignos +24
71
47
Contract termsUnique Physique +35
20
55
Signos · left barUnique Physique · right bar

The numbers

MetricSignosUnique Physique
WeighScore61.4/10061.4/100
GradeCC
Scorecard rank#294#296
Semaglutide$199/mo (6-month plan, compounded)Not disclosed
Tirzepatide$199/mo (starting dose, compounded)Not disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
Signos

Graded #294 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page
Unique Physique

Graded #296 · C

Strengths

  • Legal entity disclosed (Unique Physique, LLC) with Louisiana governing law — better than opaque DTC competitors
  • Named medical director (Reena John, DO) — uncommon at this price tier
  • Brick-and-mortar clinic in Baton Rouge, LA offers an in-person option vs ship-only competitors
  • Transparent two-tier flat pricing ($195/mo and $325/mo) — no dose-escalation surprises
  • Brand-name routing option ($25/mo) sends an Rx to your own pharmacy for Wegovy/Zepbound/Ozempic/Mounjaro

Where it loses points

  • GLP-1 drug molecules aren't named on the pricing or service pages — you can't confirm what the $195/mo and $325/mo plans contain without calling
  • Pharmacy partner not named — can't verify licensure or 503A vs 503B status
  • No FDA compounded-medication disclaimer on any audited page
  • States served not listed — only "licensed clinicians in the patient's state"
  • Non-refundable per the Terms; medication not picked up within 60 days is discarded with no refund

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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