Head-to-head · WeighScore
Signos vs Tyde Wellness
The verdict
Tyde Wellness takes it — 79.8/100 to 61.4/100.
Tyde Wellness grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Tyde Wellness is a 50-state compounded-GLP-1 and longevity telehealth platform spanning weight loss, HRT, hair, and peptides.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Signos | Tyde Wellness |
|---|---|---|
| WeighScore | 61.4/100 | 79.8/100 |
| Grade | C | C+ |
| Scorecard rank | #293 | #39 |
| Semaglutide | $199/mo (6-month plan, compounded) | $149/mo (microdose tier, all doses, compounded) |
| Tirzepatide | $199/mo (starting dose, compounded) | $249/mo (microdose tier, all doses, compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Graded #39 · C+
Strengths
- All 50 states served (full list published)
- Transparent pricing: semaglutide from $149/mo, tirzepatide from $249/mo
- LegitScript Certified with a verification link
- Five named 503A pharmacy partners with addresses: Belmar (CO), Casa (TX), Olympia (FL), Red Rock (UT), Beaker (TX)
- Free consultation; cancel-anytime subscription with no long-term commitment
Where it loses points
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
- No brand-name GLP-1s (Wegovy, Zepbound, Mounjaro, Ozempic)
- Tirzepatide priced higher than competitors offering $200-$249/mo
- Corporate address and medical director not publicly disclosed
- No NABP .pharmacy seal visible
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.