Head-to-head · WeighScore
Signos vs Transparent Meds
The verdict
Transparent Meds takes it — 61.9/100 to 61.4/100, but only just.
Transparent Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Transparent Meds is an online GLP-1 weight-care service that connects you with licensed medical providers and leads with upfront pricing: compounded weekly injections of semaglutide at an intro $149/month… Signos is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Signos | Transparent Meds |
|---|---|---|
| WeighScore | 61.4/100 | 61.9/100 |
| Grade | C | C |
| Scorecard rank | #294 | #284 |
| Semaglutide | $199/mo (6-month plan, compounded) | $229/mo (promotional rate, compounded) |
| Tirzepatide | $199/mo (starting dose, compounded) | $349/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #294 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Graded #284 · C
Strengths
- Transparent, upfront monthly pricing — intro $149/mo for compounded semaglutide and $249/mo for tirzepatide (regular $229 / $349)
- Clean, modern telehealth experience with a quick eligibility quiz and clinician review before any prescription
- HIPAA-compliant and displays a LegitScript-style verification seal
Where it loses points
- Headline prices are intro first-month fees — the regular monthly cost is higher ($229 semaglutide, $349 tirzepatide)
- Connector model that pairs you with licensed providers; it doesn't name its compounding pharmacy
- Doesn't publish the states it serves, so confirm availability before signing up
- Compounded semaglutide and tirzepatide injections only — no oral, brand-name, or insurance options
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.