Head-to-head · WeighScore
Signos vs TelePeptide
The verdict
TelePeptide takes it — 62.3/100 to 61.4/100, but only just.
TelePeptide grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. TelePeptide is a LegitScript-certified US direct-pay telehealth practice offering physician-supervised compounded GLP-1 therapy — semaglutide and tirzepatide — in injectable and oral dissolvable tablet… Signos is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Signos | TelePeptide |
|---|---|---|
| WeighScore | 61.4/100 | 62.3/100 |
| Grade | C | C |
| Scorecard rank | #293 | #273 |
| Semaglutide | $199/mo (6-month plan, compounded) | $199/mo (starting dose, annual plan, compounded oral) |
| Tirzepatide | $199/mo (starting dose, compounded) | $219/mo (starting dose, annual plan, compounded oral) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Graded #273 · C
Strengths
- LegitScript-certified (seal ID 49966407); 503A-licensed compounding pharmacies
- All-inclusive from $169/mo annual — physician eval + Rx + medication + shipping, no hidden fees
- Broadest formulation menu: injectable sema/tirz, oral dissolvable tablets, sema+naltrexone, microdose combos
- 24/7 care team messaging + regular check-ins + dosage adjustments included at every tier
- 48 states + DC coverage (excludes only AK + MS); no insurance required; cancel anytime
Where it loses points
- Compounded medications are not FDA-approved; no pharmacy partner named publicly
- Monthly billing costs more — $199/mo (monthly) vs $169/mo (annual) for semaglutide injectable; best rate requires annual prepay
- Labs not included in any plan
- Founder disclosed by first name only (Ahmed); no physician names or clinical leadership disclosed publicly
- Tirzepatide injectable at $249/mo (monthly billing) is above the compounded market average
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.