Head-to-head · WeighScore
Signos vs StackMD
The verdict
StackMD takes it — 63.4/100 to 61.4/100, but only just.
StackMD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. StackMD is a New York telehealth platform (Medical 360 HC PLLC) selling compounded semaglutide and tirzepatide, both formulated with B12 and glycine, alongside NAD+, sermorelin and other longevity peptides. Signos is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Signos | StackMD |
|---|---|---|
| WeighScore | 61.4/100 | 63.4/100 |
| Grade | C | C |
| Scorecard rank | #294 | #259 |
| Semaglutide | $199/mo (6-month plan, compounded) | $125/mo (1 mg dose, plus a separate fee, compounded) |
| Tirzepatide | $199/mo (starting dose, compounded) | $199/mo (5 mg dose, compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #294 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Graded #259 · C
Strengths
- Publishes an exact price for every dose strength rather than a single 'from' figure — semaglutide $125-$225, tirzepatide $199-$449
- Names both its legal entity (Medical 360 HC PLLC) and its prescribing telehealth partner, SamaritanMD
- No membership or platform fee — the medication price is the whole price
- States plainly that its compounded medications are 'not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality'
- Telehealth offered in all 50 states per its terms, with free discreet shipping and FSA/HSA eligibility
Where it loses points
- All sales are final — 'No refunds are issued except as described below', and dispensed medication cannot be returned
- Compounding pharmacies are never named, only 'a licensed third-party pharmacy'
- Price rises steeply with dose: tirzepatide runs $199 at 5mg to $449 at 30mg
- Billing and refunds are handled by SamaritanMD — StackMD 'has no authority to issue refunds' on its behalf
- Terms impose binding arbitration in New York and waive jury trial and class-action participation
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.