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Head-to-head · WeighScore

Sesame Care vs Southern Vitality and Weight Loss

Sesame Care
Graded #2

Higher grade

vs+22.599999999999994
Southern Vitality and Weight Loss
Graded #227

Lower grade

The verdict

Sesame Care takes it — 87.8/100 to 65.2/100.

Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSesame Care +30
84
54
Dose & formulationSesame Care +28
92
64
Clinical oversightSesame Care +7
94
87
Labs & monitoringSesame Care +30
84
54
FulfillmentSesame Care +9
80
71
Contract termsSesame Care +31
92
61
Sesame Care · left barSouthern Vitality and Weight Loss · right bar

The numbers

MetricSesame CareSouthern Vitality and Weight Loss
WeighScore87.8/10065.2/100
GradeB+C
Scorecard rank#2#227
SemaglutideFrom $149/mo (brand Wegovy pill)$199/mo (compounded)
TirzepatideBrand Zepbound (price varies)$299/mo (compounded)
CoverageNationwide marketplace1 state
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
Sesame Care

Graded #2 · B+

Strengths

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency
  • Oral routes available (Wegovy pill, Rybelsus)

Where it loses points

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Strengths

  • Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
  • Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
  • Free telehealth consult and free shipping; no membership or hidden fees
  • Bi-weekly check-ins; operating since 2012
  • Flexible monthly financing available at checkout

Where it loses points

  • This is one physical clinic in Valdosta, Georgia, not a national telehealth service — nothing here is available to a reader outside Georgia
  • The advertised 'as low as $99/month' is a semaglutide three-month starter pack ($299 paid up front), not a tirzepatide rate and not a monthly one
  • Month-to-month rates are $199 semaglutide and $299 tirzepatide
  • Compounded semaglutide and tirzepatide are not FDA-approved finished products

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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