Head-to-head · WeighScore
RxSpan MD vs Trimrose
The verdict
RxSpan MD takes it — 86.8/100 to 55.4/100.
RxSpan MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A physician-led telehealth under board-certified founder Dr. John Diaz with a broad GLP-1 menu — compounded semaglutide and tirzepatide by injection or oral capsule, plus a brand-name lane and microdosing — on transparent all-inclusive pricing to all 50 states.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | RxSpan MD | Trimrose |
|---|---|---|
| WeighScore | 86.8/100 | 55.4/100 |
| Grade | B | C |
| Scorecard rank | #4 | #440 |
| Semaglutide | From $194/mo | Not disclosed |
| Tirzepatide | $329/mo | Not disclosed |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Yes |
Graded #4 · B
Strengths
- Available in all 50 states
- Transparent, all-inclusive published pricing — consult, medication, supplies, shipping and support, cancel anytime, from ~$194/mo compounded semaglutide on an annual plan
- Both injectable and a real oral (capsule) route, plus compounded and an advertised brand-name lane
- Physician-led by a named, board-certified founder (Dr. John Diaz) with 24/7 messaging and coaching
Where it loses points
- Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
- Published pricing is for the compounded line — brand-name pricing isn’t itemized
- A prescription isn’t guaranteed — a provider reviews eligibility after checkout
Graded #440 · C
Strengths
- Free, no-cost, no-obligation online eligibility quiz before any commitment
- Offers a choice of a weekly compounded GLP-1 injection or a daily oral option
- Fully online — assessment, provider review, and home delivery with ongoing support
Where it loses points
- Runs on the CareValidate white-label platform and isn't the medical provider itself — a support@carevalidate.com address is exposed on the site
- Pricing isn't shown publicly; the cost and the specific compounded molecule appear only after you complete the eligibility quiz
- The states served, pharmacy partner and any LegitScript/503A certification aren't disclosed on the public site
- Markets 'up to 22.5% of body weight' — a trial figure for branded tirzepatide, not a guaranteed or compounded-specific outcome
- Compounded GLP-1s are not FDA-reviewed or approved — a different evidence and regulatory tier than brand-name
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.