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Head-to-head · WeighScore

RxSpan MD vs Southern Vitality and Weight Loss

RxSpan MD
Graded #4

Higher grade

vs+21.599999999999994
Southern Vitality and Weight Loss
Graded #227

Lower grade

The verdict

RxSpan MD takes it — 86.8/100 to 65.2/100.

RxSpan MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A physician-led telehealth under board-certified founder Dr. John Diaz with a broad GLP-1 menu — compounded semaglutide and tirzepatide by injection or oral capsule, plus a brand-name lane and microdosing — on transparent all-inclusive pricing to all 50 states.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRxSpan MD +32
86
54
Dose & formulationRxSpan MD +25
89
64
Clinical oversightRxSpan MD +1
88
87
Labs & monitoringRxSpan MD +29
83
54
FulfillmentRxSpan MD +18
89
71
Contract termsRxSpan MD +24
85
61
RxSpan MD · left barSouthern Vitality and Weight Loss · right bar

The numbers

MetricRxSpan MDSouthern Vitality and Weight Loss
WeighScore86.8/10065.2/100
GradeBC
Scorecard rank#4#227
SemaglutideFrom $194/mo$199/mo (compounded)
Tirzepatide$329/mo$299/mo (compounded)
CoverageAll 50 states1 state
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
RxSpan MD

Graded #4 · B

Strengths

  • Available in all 50 states
  • Transparent, all-inclusive published pricing — consult, medication, supplies, shipping and support, cancel anytime, from ~$194/mo compounded semaglutide on an annual plan
  • Both injectable and a real oral (capsule) route, plus compounded and an advertised brand-name lane
  • Physician-led by a named, board-certified founder (Dr. John Diaz) with 24/7 messaging and coaching

Where it loses points

  • Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
  • Published pricing is for the compounded line — brand-name pricing isn’t itemized
  • A prescription isn’t guaranteed — a provider reviews eligibility after checkout

Strengths

  • Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
  • Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
  • Free telehealth consult and free shipping; no membership or hidden fees
  • Bi-weekly check-ins; operating since 2012
  • Flexible monthly financing available at checkout

Where it loses points

  • This is one physical clinic in Valdosta, Georgia, not a national telehealth service — nothing here is available to a reader outside Georgia
  • The advertised 'as low as $99/month' is a semaglutide three-month starter pack ($299 paid up front), not a tirzepatide rate and not a monthly one
  • Month-to-month rates are $199 semaglutide and $299 tirzepatide
  • Compounded semaglutide and tirzepatide are not FDA-approved finished products

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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