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Head-to-head · WeighScore

RxSpan MD vs SkinnyRx

RxSpan MD
Graded #4

Higher grade

vs+26.299999999999997
SkinnyRx
Graded #247

Lower grade

The verdict

RxSpan MD takes it — 86.8/100 to 60.5/100.

RxSpan MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A physician-led telehealth under board-certified founder Dr. John Diaz with a broad GLP-1 menu — compounded semaglutide and tirzepatide by injection or oral capsule, plus a brand-name lane and microdosing — on transparent all-inclusive pricing to all 50 states.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRxSpan MD +34
86
52
Dose & formulationRxSpan MD +1
89
88
Clinical oversightRxSpan MD +33
88
55
Labs & monitoringRxSpan MD +43
83
40
FulfillmentRxSpan MD +7
89
82
Contract termsRxSpan MD +47
85
38
RxSpan MD · left barSkinnyRx · right bar

The numbers

MetricRxSpan MDSkinnyRx
WeighScore86.8/10060.5/100
GradeBC
Scorecard rank#4#247
SemaglutideFrom $194/mo$349/mo month-to-month (compounded; the advertised rate is a 12-month prepay)
Tirzepatide$329/mo$399/mo month-to-month (compounded; the advertised rate is a 12-month prepay)
CoverageAll 50 states47 states + DC (not Alabama, Louisiana or Mississippi)
Brand-name accessYesCompounded only
Oral / sublingualYesYes
RxSpan MD

Graded #4 · B

Strengths

  • Available in all 50 states
  • Transparent, all-inclusive published pricing — consult, medication, supplies, shipping and support, cancel anytime, from ~$194/mo compounded semaglutide on an annual plan
  • Both injectable and a real oral (capsule) route, plus compounded and an advertised brand-name lane
  • Physician-led by a named, board-certified founder (Dr. John Diaz) with 24/7 messaging and coaching

Where it loses points

  • Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
  • Published pricing is for the compounded line — brand-name pricing isn’t itemized
  • A prescription isn’t guaranteed — a provider reviews eligibility after checkout
SkinnyRx

Graded #247 · C

FDAWarning letter issued to Lean Rx, Inc. dba SkinnyRx in February 2026. See the FDA warning-letter database.

Strengths

  • Both molecules by both routes: semaglutide and tirzepatide as injections, tirzepatide as a tablet on the identical term ladder, plus a separate low-dose line with its own page
  • The full term ladder — every rung, both molecules — is on the product page before any medical intake, which is more than most of this board discloses after one
  • Terms are concrete rather than gestural: free shipping, unlimited provider messaging, a 90-day money-back guarantee, and no charge at all if a clinician finds you ineligible
  • The state exclusions are published rather than discovered at checkout — 47 states plus DC, with Alabama, Louisiana and Mississippi named

Where it loses points

  • FDA issued Lean Rx, Inc. dba SkinnyRx a warning letter in February 2026; the letter is public in FDA's warning-letter database
  • The advertised "$199/mo" and "$299/mo" are twelve-month rates by construction — the site's own price code drops the one-month rung before picking a headline — so the monthly rates are $349 semaglutide and $399 tirzepatide
  • Those rungs are a single up-front charge, not a smaller bill: $2,388 for the semaglutide year and $3,588 for the tirzepatide year, taken on day one and auto-renewing each term, with membership fees stated as non-refundable
  • The microdose line costs the SAME as full dose at every term the two share, and its floor is HIGHER — $229 against $199 on semaglutide, $319 against $299 on tirzepatide — because the low-dose plans stop at eight months rather than twelve
  • No brand-name product is actually purchasable: Ozempic, Wegovy, Mounjaro and Zepbound all carry a null price, both pill products are out of stock, and the only priced brand path is a $49/mo membership plus a medication cost that is never published
  • Compounded semaglutide and tirzepatide are not FDA-approved and are not generic equivalents of the brand drugs
  • Fulfillment is disclosed only as a category: "503A pharmacies", never a facility, never a city, and no medical director is named for the programme anywhere on the site — so the two things that decide whether a compounded vial is trustworthy are the two things this seller does not publish
  • Labs and monitoring are simply absent from the site: nothing states whether baseline or follow-up bloodwork is required, included in the membership, or billed on top of it
  • Alabama, Louisiana and Mississippi are excluded, so three states' readers cannot buy at any price on this ladder

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 508 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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