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Head-to-head · WeighScore

RxSpan MD vs Sesame Care

RxSpan MD
Site position #6

Lower grade

Sesame Care
Site position #2

Higher grade

The verdict

Sesame Care takes it — 87.8/100 to 84.3/100.

Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

We may earn a commission through these links, at no extra cost to you. Commercial relationships affect placement, but never the WeighScore or our editorial findings. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRxSpan MD +2
86
84
Dose & formulationSesame Care +3
89
92
Clinical oversightSesame Care +6
88
94
Labs & monitoringSesame Care +1
83
84
FulfillmentRxSpan MD +9
89
80
Contract termsSesame Care +39
53
92
RxSpan MD · top barSesame Care · bottom bar

The numbers

Swipe or scroll to compare both providers.

MetricRxSpan MDSesame Care
WeighScore84.3/10087.8/100
GradeBB+
Site position#6#2
Semaglutide$249/mo month-to-month ($219 on three months, $199 on six, $194 on twelve)Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year)
Tirzepatide$329/mo month-to-month ($309 on three months, $289 on six, $269 on twelve)Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days
CoverageConfirm treatment availability during intakeNationwide marketplace
Brand-name accessYesYes
Oral / sublingualYesYes
RxSpan MD

Site position #6 · B

Strengths

  • Public catalog offers compounded injections, oral options and brand-name programs
  • Regular monthly injection pricing of $249 semaglutide and $329 tirzepatide
  • Catalog states consultation, medication, supplies, shipping and support are included
  • Names physician founder Dr. John Diaz and describes licensed-physician review

Where it loses points

  • Lowest advertised monthly equivalents require prepaid terms and a promotional code
  • Annual promotions automatically renew
  • Public terms do not establish a refund schedule for unused prepaid treatment
  • Compounded semaglutide and tirzepatide are not FDA-approved
Sesame Care

Site position #2 · B+

Strengths

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency
  • Oral routes available (Wegovy pill, Rybelsus)

Where it loses points

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Featured provider

Sesame Care

Sesame Care scores 87.8/100 (B+). An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

Commercial relationships affect this placement. The score comparison above is separate.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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