Head-to-head · WeighScore
RxPros vs Signos
The verdict
RxPros takes it — 69.3/100 to 61.4/100.
RxPros grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. RxPros (rxpros.com) is a Wyoming-incorporated compounded GLP-1 telehealth platform (RxPros LLC, 1309 Coffeen Ave Ste 15880, Sheridan, WY 82801).
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | RxPros | Signos |
|---|---|---|
| WeighScore | 69.3/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #134 | #295 |
| Semaglutide | $100/mo (annual plan, compounded) | $199/mo (6-month plan, compounded) |
| Tirzepatide | $145/mo (annual plan, compounded) | $199/mo (starting dose, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #134 · C
Strengths
- $99.99/month compounded semaglutide — among the cheapest in the US compounded telehealth market
- $144.97/month compounded tirzepatide — at the lower end of the compounded tirzepatide range
- LegitScript Certified
- Named legal entity (RxPros LLC) with a physical Wyoming address
- Overnight cold-packed shipping disclosed — important for GLP-1 cold-chain integrity
Where it loses points
- Per-state availability not listed — verify your state ships before committing
- Specific 503A pharmacy partners not named
- Lab work not included as standard
- LegitScript certification number not displayed (seal only)
- Lowest headline prices ($99.99 sema / $144.97 tirz) require annual prepay; intro-first-month/quarterly tier is $134.99 sema / $224.99 tirz
Graded #295 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.