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Head-to-head · WeighScore

RxPepsDirect vs ZYP Medical

RxPepsDirect
Graded #140

Lower grade

vs+5.8999999999999915
ZYP Medical
Graded #62

Higher grade

The verdict

ZYP Medical takes it — 74.6/100 to 68.7/100.

ZYP Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRxPepsDirect +6
86
80
Dose & formulationZYP Medical +19
64
83
Clinical oversightZYP Medical +17
69
86
Labs & monitoringZYP Medical +1
52
53
FulfillmentRxPepsDirect +4
70
66
Contract termsZYP Medical +6
55
61
RxPepsDirect · left barZYP Medical · right bar

The numbers

MetricRxPepsDirectZYP Medical
WeighScore68.7/10074.6/100
GradeCC
Scorecard rank#140#62
Semaglutide$79/mo (starting dose, visit fee and shipping included, compounded)$150/mo
Tirzepatide$99/mo (starting dose, visit fee and shipping included, compounded)$233/mo
Coverage28 states6 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
RxPepsDirect

Graded #140 · C

Strengths

  • Every component of the price is published on the site — the vial tiers, the flat visit charge and the flat overnight delivery — so the all-in monthly cost can be worked out before ordering
  • No subscription and no commitment: you pay per order, and one visit charge covers up to three peptides on the same prescription
  • Real 503A telehealth Rx — licensed NP/PA prescribers under medical director Dr. Jonathan Snipes (NPI 1821250077), dispensed by Optimal Balance Pharmacy, Texas Board #34829
  • Independent batch COA testing by Eagle Analytical (FDA-registered, A2LA ISO 17025): 54/54 sterility and endotoxin passes published publicly
  • Ships pre-reconstituted by FedEx overnight with syringes, alcohol wipes and a reusable cooled travel case included

Where it loses points

  • The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
  • Higher doses need more than one vial a month and the site publishes no price for the dose you titrate up to, so the figure above is a floor
  • Minimal clinical oversight: a roughly two-minute asynchronous intake, no live video consult, no labs required and no published dose-escalation monitoring
  • No LegitScript certification, and the company was founded in 2026 with no public track record or outcomes data
  • Only 28 states and DC — California is excluded, along with most of the Southeast (AL, AR, GA, MS, NC, SC, TN, VA)
ZYP Medical

Graded #62 · C

Strengths

  • Transparent flat-rate pricing including medication and shipping with no hidden fees
  • Low $50 initial one-hour consultation
  • Offers both injectable and oral tirzepatide options
  • No membership fees and pricing decreases as treatment progresses
  • Care from a board-certified family nurse practitioner

Where it loses points

  • Compounded medications are not FDA-approved
  • Available in only six states (NE, IA, SD, KS, CO, AZ)
  • Cash-pay only; no insurance noted
  • No named compounding pharmacy partner disclosed
  • No LegitScript certification shown on site

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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