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Head-to-head · WeighScore

RxPepsDirect vs Tuyo Health

RxPepsDirect
Graded #150

Lower grade

vs+8
Tuyo Health
Graded #51

Higher grade

The verdict

Tuyo Health takes it — 76.5/100 to 68.5/100.

Tuyo Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Tuyo Health (tuyohealth.com) is a US telehealth weight-loss program founded by Dr.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRxPepsDirect +7
85
78
Dose & formulationTuyo Health +21
64
85
Clinical oversightTuyo Health +7
69
76
Labs & monitoringTuyo Health +36
52
88
FulfillmentRxPepsDirect +1
70
69
Contract termsRxPepsDirect +14
55
41
RxPepsDirect · left barTuyo Health · right bar

The numbers

MetricRxPepsDirectTuyo Health
WeighScore68.5/10076.5/100
GradeCC
Scorecard rank#150#51
Semaglutide$79/mo (starting dose, visit fee and shipping included, compounded)$155/mo
Tirzepatide$99/mo (starting dose, visit fee and shipping included, compounded)$279/mo
Coverage28 statesCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
RxPepsDirect

Graded #150 · C

Strengths

  • Every component of the price is published on the site — the vial tiers, the flat visit charge and the flat overnight delivery — so the all-in monthly cost can be worked out before ordering
  • No subscription and no commitment: you pay per order, and one visit charge covers up to three peptides on the same prescription
  • Real 503A telehealth Rx — licensed NP/PA prescribers under medical director Dr. Jonathan Snipes (NPI 1821250077), dispensed by Optimal Balance Pharmacy, Texas Board #34829
  • Independent batch COA testing by Eagle Analytical (FDA-registered, A2LA ISO 17025): 54/54 sterility and endotoxin passes published publicly
  • Ships pre-reconstituted by FedEx overnight with syringes, alcohol wipes and a reusable cooled travel case included

Where it loses points

  • The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
  • Higher doses need more than one vial a month and the site publishes no price for the dose you titrate up to, so the figure above is a floor
  • Minimal clinical oversight: a roughly two-minute asynchronous intake, no live video consult, no labs required and no published dose-escalation monitoring
  • No LegitScript certification, and the company was founded in 2026 with no public track record or outcomes data
  • Only 28 states and DC — California is excluded, along with most of the Southeast (AL, AR, GA, MS, NC, SC, TN, VA)
Tuyo Health

Graded #51 · C

Strengths

  • Low starting price of 155 dollars per month for compounded semaglutide, all-inclusive
  • Offers both compounded and brand-name Wegovy and Zepbound, with an insurance option
  • Free same-week shipping, complimentary consults and periodic lab work included

Where it loses points

  • Service-area states not published
  • No specific compounding pharmacy named on the site
  • Brand-name plans add a separate 99 dollar membership fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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