Head-to-head · WeighScore
RxPepsDirect vs Trillium Meds
The verdict
Trillium Meds takes it — 69.4/100 to 68.7/100, but only just.
Trillium Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Trillium Meds is a small, owner-operated telehealth platform based in Portland, OR that connects patients with independent licensed providers and FDA-registered compounding pharmacies for compounded… RxPepsDirect is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | RxPepsDirect | Trillium Meds |
|---|---|---|
| WeighScore | 68.7/100 | 69.4/100 |
| Grade | C | C |
| Scorecard rank | #140 | #124 |
| Semaglutide | $79/mo (starting dose, visit fee and shipping included, compounded) | $119/mo (3-month plan, compounded) |
| Tirzepatide | $99/mo (starting dose, visit fee and shipping included, compounded) | $199/mo (3-month plan, compounded) |
| Coverage | 28 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #140 · C
Strengths
- Every component of the price is published on the site — the vial tiers, the flat visit charge and the flat overnight delivery — so the all-in monthly cost can be worked out before ordering
- No subscription and no commitment: you pay per order, and one visit charge covers up to three peptides on the same prescription
- Real 503A telehealth Rx — licensed NP/PA prescribers under medical director Dr. Jonathan Snipes (NPI 1821250077), dispensed by Optimal Balance Pharmacy, Texas Board #34829
- Independent batch COA testing by Eagle Analytical (FDA-registered, A2LA ISO 17025): 54/54 sterility and endotoxin passes published publicly
- Ships pre-reconstituted by FedEx overnight with syringes, alcohol wipes and a reusable cooled travel case included
Where it loses points
- The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
- Higher doses need more than one vial a month and the site publishes no price for the dose you titrate up to, so the figure above is a floor
- Minimal clinical oversight: a roughly two-minute asynchronous intake, no live video consult, no labs required and no published dose-escalation monitoring
- No LegitScript certification, and the company was founded in 2026 with no public track record or outcomes data
- Only 28 states and DC — California is excluded, along with most of the Southeast (AL, AR, GA, MS, NC, SC, TN, VA)
Graded #124 · C
Strengths
- LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
- All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
- Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
- Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
- Klarna and Affirm financing available; pause anytime with no long-term commitment required
Where it loses points
- No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
- Small single-operator platform may limit capacity and support consistency as patient volume grows
- Compounded medications are not FDA-approved; newer platform with limited long-term public track record
- Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
- No live video consult disclosed; async intake-form-based provider review by external licensed provider network
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.