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Head-to-head · WeighScore

RxPepsDirect vs StackMD

RxPepsDirect
Graded #146

Higher grade

vs+5.300000000000004
StackMD
Graded #259

Lower grade

The verdict

RxPepsDirect takes it — 68.7/100 to 63.4/100.

RxPepsDirect grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform offering semaglutide/B12 from $25/vial and tirzepatide/B12 from $45/vial, dispensed through Optimal Balance Pharmacy (503A,…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRxPepsDirect +28
74
46
Dose & formulationRxPepsDirect +10
64
54
Clinical oversightStackMD +9
69
78
Labs & monitoringRxPepsDirect +10
72
62
FulfillmentStackMD +19
70
89
Contract termsStackMD +14
55
69
RxPepsDirect · left barStackMD · right bar

The numbers

MetricRxPepsDirectStackMD
WeighScore68.7/10063.4/100
GradeCC
Scorecard rank#146#259
Semaglutide$64/mo (starting dose, plus a separate fee, compounded)$125/mo (1 mg dose, plus a separate fee, compounded)
Tirzepatide$84/mo (starting dose, plus a separate fee, compounded)$199/mo (5 mg dose, compounded)
Coverage28 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
RxPepsDirect

Graded #146 · C

Strengths

  • Industry-lowest GLP-1 pricing: compounded semaglutide from $25/vial, tirzepatide from $45/vial — no subscription or recurring commitment required
  • Real 503A telehealth Rx: licensed NP/PA prescribers + MD medical director (Dr. Jonathan Snipes, NPI 1821250077); patient-specific Rx dispensed by
  • FedEx overnight shipping at $15 flat; ships pre-reconstituted and includes syringes, alcohol wipes, and reusable cooled travel case
  • Independent batch COA testing by Eagle Analytical (FDA-registered, A2LA ISO 17025): 54/54 sterility and endotoxin passes published publicly on
  • No subscription required; $39 flat visit fee covers up to 3 peptides per Rx; pay per vial with no ongoing commitment

Where it loses points

  • No LegitScript certification; company founded 2026 — no public track record or long-term patient-outcomes data
  • Minimal clinical oversight: $39 asynchronous intake form only — no live video consult required, no labs mandated, no monitoring protocol; lowest
  • Per-vial pricing makes true monthly cost opaque; every refill costs another $39 visit fee on top of vial price and $15 shipping
  • Only 28 states + DC; excludes California, most of the Southeast (AL, AR, GA, MS, NC, SC, TN, VA), and parts of Midwest
  • No coaching, labs, dietitian support, or clinical monitoring included at any tier — purely prescription + dispensing
StackMD

Graded #259 · C

Strengths

  • Publishes an exact price for every dose strength rather than a single 'from' figure — semaglutide $125-$225, tirzepatide $199-$449
  • Names both its legal entity (Medical 360 HC PLLC) and its prescribing telehealth partner, SamaritanMD
  • No membership or platform fee — the medication price is the whole price
  • States plainly that its compounded medications are 'not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality'
  • Telehealth offered in all 50 states per its terms, with free discreet shipping and FSA/HSA eligibility

Where it loses points

  • All sales are final — 'No refunds are issued except as described below', and dispensed medication cannot be returned
  • Compounding pharmacies are never named, only 'a licensed third-party pharmacy'
  • Price rises steeply with dose: tirzepatide runs $199 at 5mg to $449 at 30mg
  • Billing and refunds are handled by SamaritanMD — StackMD 'has no authority to issue refunds' on its behalf
  • Terms impose binding arbitration in New York and waive jury trial and class-action participation

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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