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Head-to-head · WeighScore

RxPepsDirect vs Shapely

RxPepsDirect
Graded #146

Higher grade

vs+3.299999999999997
Shapely
Graded #225

Lower grade

The verdict

RxPepsDirect takes it — 68.7/100 to 65.4/100.

RxPepsDirect grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform offering semaglutide/B12 from $25/vial and tirzepatide/B12 from $45/vial, dispensed through Optimal Balance Pharmacy (503A,…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRxPepsDirect +29
74
45
Dose & formulationRxPepsDirect +11
64
53
Clinical oversightShapely +25
69
94
Labs & monitoringShapely +1
72
73
FulfillmentShapely +8
70
78
Contract termsEven
55
55
RxPepsDirect · left barShapely · right bar

The numbers

MetricRxPepsDirectShapely
WeighScore68.7/10065.4/100
GradeCC
Scorecard rank#146#225
Semaglutide$64/mo (starting dose, plus a separate fee, compounded)Not disclosed
Tirzepatide$84/mo (starting dose, plus a separate fee, compounded)Not disclosed
Coverage28 states4 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
RxPepsDirect

Graded #146 · C

Strengths

  • Industry-lowest GLP-1 pricing: compounded semaglutide from $25/vial, tirzepatide from $45/vial — no subscription or recurring commitment required
  • Real 503A telehealth Rx: licensed NP/PA prescribers + MD medical director (Dr. Jonathan Snipes, NPI 1821250077); patient-specific Rx dispensed by
  • FedEx overnight shipping at $15 flat; ships pre-reconstituted and includes syringes, alcohol wipes, and reusable cooled travel case
  • Independent batch COA testing by Eagle Analytical (FDA-registered, A2LA ISO 17025): 54/54 sterility and endotoxin passes published publicly on
  • No subscription required; $39 flat visit fee covers up to 3 peptides per Rx; pay per vial with no ongoing commitment

Where it loses points

  • No LegitScript certification; company founded 2026 — no public track record or long-term patient-outcomes data
  • Minimal clinical oversight: $39 asynchronous intake form only — no live video consult required, no labs mandated, no monitoring protocol; lowest
  • Per-vial pricing makes true monthly cost opaque; every refill costs another $39 visit fee on top of vial price and $15 shipping
  • Only 28 states + DC; excludes California, most of the Southeast (AL, AR, GA, MS, NC, SC, TN, VA), and parts of Midwest
  • No coaching, labs, dietitian support, or clinical monitoring included at any tier — purely prescription + dispensing
Shapely

Graded #225 · C

Strengths

  • Founded by Dr. Justin Zaghi, MD/MBA — Harvard-trained, board-certified in internal medicine and obesity medicine, with Medical Director Ana Lisa
  • Brand-name GLP-1s (Wegovy, Ozempic, Zepbound, Mounjaro, Foundayo) covered by major PPO and Medicare at copay
  • Compounded semaglutide from $99/month with free 2-day shipping, syringes, and supplies included via 503A/503B pharmacy
  • 1:1 registered dietitian (RDN) and monthly video provider visits included in every plan; unlimited chat and app support
  • Cellular smart scale provided to qualifying patients for ongoing weight tracking throughout the program

Where it loses points

  • Currently available only in California, Florida, New York, and Texas — 46 states unserved despite announced expansion
  • Telehealth subscription ($99/mo self-pay, $49 first-month promo) is charged separately from compounded medication cost
  • Labs not included — $75 flat rate for uninsured patients; baseline bloodwork may be required before prescribing
  • No LegitScript certification found on any public page
  • Compounding pharmacy partner not named publicly; 503A/503B status claimed but specific pharmacy undisclosed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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