Head-to-head · WeighScore
RxPepsDirect vs Sesame Care
The verdict
Sesame Care takes it — 87.8/100 to 68.7/100.
Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | RxPepsDirect | Sesame Care |
|---|---|---|
| WeighScore | 68.7/100 | 87.8/100 |
| Grade | C | B+ |
| Scorecard rank | #146 | #2 |
| Semaglutide | $64/mo (starting dose, plus a separate fee, compounded) | From $149/mo (brand Wegovy pill) |
| Tirzepatide | $84/mo (starting dose, plus a separate fee, compounded) | Brand Zepbound (price varies) |
| Coverage | 28 states | Nationwide marketplace |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #146 · C
Strengths
- Industry-lowest GLP-1 pricing: compounded semaglutide from $25/vial, tirzepatide from $45/vial — no subscription or recurring commitment required
- Real 503A telehealth Rx: licensed NP/PA prescribers + MD medical director (Dr. Jonathan Snipes, NPI 1821250077); patient-specific Rx dispensed by
- FedEx overnight shipping at $15 flat; ships pre-reconstituted and includes syringes, alcohol wipes, and reusable cooled travel case
- Independent batch COA testing by Eagle Analytical (FDA-registered, A2LA ISO 17025): 54/54 sterility and endotoxin passes published publicly on
- No subscription required; $39 flat visit fee covers up to 3 peptides per Rx; pay per vial with no ongoing commitment
Where it loses points
- No LegitScript certification; company founded 2026 — no public track record or long-term patient-outcomes data
- Minimal clinical oversight: $39 asynchronous intake form only — no live video consult required, no labs mandated, no monitoring protocol; lowest
- Per-vial pricing makes true monthly cost opaque; every refill costs another $39 visit fee on top of vial price and $15 shipping
- Only 28 states + DC; excludes California, most of the Southeast (AL, AR, GA, MS, NC, SC, TN, VA), and parts of Midwest
- No coaching, labs, dietitian support, or clinical monitoring included at any tier — purely prescription + dispensing
Graded #2 · B+
Strengths
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
- Oral routes available (Wegovy pill, Rybelsus)
Where it loses points
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.