Head-to-head · WeighScore
RxPepsDirect vs RxSpan MD
The verdict
RxSpan MD takes it — 86.8/100 to 68.7/100.
RxSpan MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A physician-led telehealth under board-certified founder Dr. John Diaz with a broad GLP-1 menu — compounded semaglutide and tirzepatide by injection or oral capsule, plus a brand-name lane and microdosing — on transparent all-inclusive pricing to all 50 states.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | RxPepsDirect | RxSpan MD |
|---|---|---|
| WeighScore | 68.7/100 | 86.8/100 |
| Grade | C | B |
| Scorecard rank | #140 | #4 |
| Semaglutide | $79/mo (starting dose, visit fee and shipping included, compounded) | From $194/mo |
| Tirzepatide | $99/mo (starting dose, visit fee and shipping included, compounded) | $329/mo |
| Coverage | 28 states | All 50 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #140 · C
Strengths
- Every component of the price is published on the site — the vial tiers, the flat visit charge and the flat overnight delivery — so the all-in monthly cost can be worked out before ordering
- No subscription and no commitment: you pay per order, and one visit charge covers up to three peptides on the same prescription
- Real 503A telehealth Rx — licensed NP/PA prescribers under medical director Dr. Jonathan Snipes (NPI 1821250077), dispensed by Optimal Balance Pharmacy, Texas Board #34829
- Independent batch COA testing by Eagle Analytical (FDA-registered, A2LA ISO 17025): 54/54 sterility and endotoxin passes published publicly
- Ships pre-reconstituted by FedEx overnight with syringes, alcohol wipes and a reusable cooled travel case included
Where it loses points
- The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
- Higher doses need more than one vial a month and the site publishes no price for the dose you titrate up to, so the figure above is a floor
- Minimal clinical oversight: a roughly two-minute asynchronous intake, no live video consult, no labs required and no published dose-escalation monitoring
- No LegitScript certification, and the company was founded in 2026 with no public track record or outcomes data
- Only 28 states and DC — California is excluded, along with most of the Southeast (AL, AR, GA, MS, NC, SC, TN, VA)
Graded #4 · B
Strengths
- Available in all 50 states
- Transparent, all-inclusive published pricing — consult, medication, supplies, shipping and support, cancel anytime, from ~$194/mo compounded semaglutide on an annual plan
- Both injectable and a real oral (capsule) route, plus compounded and an advertised brand-name lane
- Physician-led by a named, board-certified founder (Dr. John Diaz) with 24/7 messaging and coaching
Where it loses points
- Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
- Published pricing is for the compounded line — brand-name pricing isn’t itemized
- A prescription isn’t guaranteed — a provider reviews eligibility after checkout
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.