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Head-to-head · WeighScore

Roen Rx vs SynergenX Health

Roen Rx
Graded #348

Higher grade

vs+0.8000000000000043
SynergenX Health
Graded #374

Lower grade

The verdict

Roen Rx takes it — 59.2/100 to 58.4/100, but only just.

Roen Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Roen Rx offers compounded semaglutide as well as brand-name Ozempic, Wegovy, Zepbound, and Mounjaro with insurance coordination. SynergenX Health is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSynergenX Health +7
39
46
Dose & formulationRoen Rx +25
77
52
Clinical oversightRoen Rx +8
74
66
Labs & monitoringSynergenX Health +33
53
86
FulfillmentRoen Rx +12
67
55
Contract termsSynergenX Health +6
41
47
Roen Rx · left barSynergenX Health · right bar

The numbers

MetricRoen RxSynergenX Health
WeighScore59.2/10058.4/100
GradeCC
Scorecard rank#348#374
Semaglutide$151/mo (3-month plan, plus a separate fee, compounded)$150/mo (starting dose, plus a separate fee, compounded)
Tirzepatide$216/mo (plus a separate fee, compounded)Not disclosed
CoverageCoverage not published10 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Roen Rx

Graded #348 · C

Strengths

  • Insurance coordination for brand-name GLP-1s — as low as $25/mo
  • Both compounded and brand-name options
  • LegitScript approved with Compounded USA badge
  • Compounded semaglutide from $151/mo quarterly
  • Also offers primary care, mental health, and other specialties

Where it loses points

  • State availability not publicly disclosed
  • Insurance coordination may not work for all plans
  • Broader platform (ED, hair loss, skincare, birth control)
  • Requires a separate membership (first month $39); GLP-1 medications are NOT included in the membership fee - medication is billed on top
SynergenX Health

Graded #374 · C

Strengths

  • Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
  • Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
  • Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
  • Nutrition counseling and lifestyle planning included as part of personalized treatment program
  • Free weight-loss consultation option available before committing to paid evaluation

Where it loses points

  • Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
  • Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
  • Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
  • Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
  • No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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