Head-to-head · WeighScore
Roen Rx vs Ryze Rx
The verdict
Roen Rx takes it — 59/100 to 58.2/100, but only just.
Roen Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Roen Rx offers compounded semaglutide as well as brand-name Ozempic, Wegovy, Zepbound, and Mounjaro with insurance coordination. Ryze Rx is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Roen Rx | Ryze Rx |
|---|---|---|
| WeighScore | 59/100 | 58.2/100 |
| Grade | C | C |
| Scorecard rank | #350 | #376 |
| Semaglutide | $151/mo (3-month plan, plus a separate fee, compounded) | $199/mo (starting dose, 3 month plan, compounded) |
| Tirzepatide | $216/mo (plus a separate fee, compounded) | $199/mo (starting dose, 3 month plan, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #350 · C
Strengths
- Insurance coordination for brand-name GLP-1s — as low as $25/mo
- Both compounded and brand-name options
- LegitScript approved with Compounded USA badge
- Compounded semaglutide from $151/mo quarterly
- Also offers primary care, mental health, and other specialties
Where it loses points
- State availability not publicly disclosed
- Insurance coordination may not work for all plans
- Broader platform (ED, hair loss, skincare, birth control)
- Requires a separate membership (first month $39); GLP-1 medications are NOT included in the membership fee - medication is billed on top
Graded #376 · C
Strengths
- Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
- Physician consultation, ongoing clinical support and discreet shipping included with each prescription
- Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
- Free shipping, 24hr prescription turnaround, FSA/HSA eligible; care advertised in all 50 states
Where it loses points
- Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
- Pharmacy partners not named - only 'US-licensed compounding pharmacies'
- Homepage advertises GLP-1s 'from $149/mo' but the catalog lists $199/mo
- On-site '4.9/5, 2,400+ reviews' is self-reported, not an independently verified rating
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.