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Head-to-head · WeighScore

Ro vs Signos

Ro
Graded #38

Higher grade

vs+18.800000000000004
Signos
Graded #294

Lower grade

The verdict

Ro takes it — 80.2/100 to 61.4/100.

Ro grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A heavyweight platform with brand-name access — but opaque compounded pricing drags its score.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRo +24
68
44
Dose & formulationRo +22
86
64
Clinical oversightRo +2
86
84
Labs & monitoringRo +11
82
71
FulfillmentRo +13
84
71
Contract termsRo +60
80
20
Ro · left barSignos · right bar

The numbers

MetricRoSignos
WeighScore80.2/10061.4/100
GradeB−C
Scorecard rank#38#294
SemaglutideNot disclosed$199/mo (6-month plan, compounded)
TirzepatideNot disclosed$199/mo (starting dose, compounded)
CoverageMulti-stateCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
Ro

Graded #38 · B−

Strengths

  • Brand-name access + insurance support
  • Oral options
  • Well-funded platform

Where it loses points

  • Does not disclose compounded pricing up front
  • Premium positioning
Signos

Graded #294 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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