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Head-to-head · WeighScore

Risen Labs vs Signos

Risen Labs
Graded #403

Lower grade

vs+4.199999999999996
Signos
Graded #293

Higher grade

The verdict

Signos takes it — 61.4/100 to 57.2/100.

Signos grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with…

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Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRisen Labs +1
45
44
Dose & formulationSignos +24
40
64
Clinical oversightSignos +5
79
84
Labs & monitoringSignos +7
64
71
FulfillmentSignos +3
68
71
Contract termsRisen Labs +35
55
20
Risen Labs · left barSignos · right bar

The numbers

MetricRisen LabsSignos
WeighScore57.2/10061.4/100
GradeCC
Scorecard rank#403#293
SemaglutideNot disclosed$199/mo (6-month plan, compounded)
TirzepatideNot disclosed$199/mo (starting dose, compounded)
Coverage2 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Risen Labs

Graded #403 · C

Strengths

  • Names its compounding pharmacy (Olympia Pharmacy, a 503A compounding pharmacy) and legal entity (Risen Labs LLC)
  • Offers compounded semaglutide and tirzepatide as clinician-guided once-weekly injections
  • Focused clinical intake covering weight loss, men's health, and hormone protocols

Where it loses points

  • GLP-1 pricing is not published; it appears only after you complete the clinical intake
  • Available only to patients in New York and Colorado
  • Compounded semaglutide and tirzepatide are not FDA-approved finished products
  • No LegitScript certification is displayed on the site
Signos

Graded #293 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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