Head-to-head · WeighScore
Rex MD vs Southern Vitality and Weight Loss
The verdict
Southern Vitality and Weight Loss takes it — 74.2/100 to 70.2/100.
Southern Vitality and Weight Loss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Southern Vitality and Weight Loss is a physician-supervised telehealth weight-loss program (operating since 2012) offering compounded semaglutide and tirzepatide starting as low as $99/mo, plus vitamin…
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Rex MD | Southern Vitality and Weight Loss |
|---|---|---|
| WeighScore | 70.2/100 | 74.2/100 |
| Grade | C | C |
| Scorecard rank | #109 | #67 |
| Semaglutide | $199/mo (brand-name) | $99/mo (starting dose, compounded) |
| Tirzepatide | $349/mo (brand Zepbound) | $99/mo (starting dose, compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #109 · C
Strengths
- Flat $199/mo program bundles consult, medication and overnight shipping
- Brand-name semaglutide and Zepbound vials, not just compounded
- Serves all 50 states, fully online
- LegitScript certified with US-based, state-licensed providers
- Backed by parent company LifeMD
Where it loses points
- Does not accept insurance
- Marketed primarily to men via a men's-health platform
- Zepbound vial cost rises with dose titration
- Branded-only program costs more than compounded options
Graded #67 · C
Strengths
- Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
- Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
- Free telehealth consult and free shipping; no membership or hidden fees
- Bi-weekly check-ins; operating since 2012
- Flexible monthly financing available at checkout
Where it loses points
- All sales final once a prescription is approved and sent to the pharmacy
- States of operation not published
- Not LegitScript-certified (no certification displayed)
- Prescribing medical group not named (only "licensed providers")
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.