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Head-to-head · WeighScore

RedBox Rx vs Signos

RedBox Rx
Graded #111

Higher grade

vs+8.800000000000004
Signos
Graded #294

Lower grade

The verdict

RedBox Rx takes it — 70.2/100 to 61.4/100.

RedBox Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. RedBox Rx is a US telehealth pharmacy (parent company Hy-Vee) offering compounded GLP-1 weight management with flat, dose-independent pricing.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSignos +2
42
44
Dose & formulationRedBox Rx +19
83
64
Clinical oversightRedBox Rx +9
93
84
Labs & monitoringRedBox Rx +13
84
71
FulfillmentRedBox Rx +1
72
71
Contract termsRedBox Rx +21
41
20
RedBox Rx · left barSignos · right bar

The numbers

MetricRedBox RxSignos
WeighScore70.2/10061.4/100
GradeCC
Scorecard rank#111#294
Semaglutide$269/mo (all doses, 6-month plan, compounded)$199/mo (6-month plan, compounded)
Tirzepatide$429/mo$199/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
RedBox Rx

Graded #111 · C

Strengths

  • Flat, dose-independent pricing on both semaglutide and tirzepatide
  • Offers both weekly injections and daily oral tablets
  • Includes unlimited provider follow-ups, a metabolic panel and a dietitian session
  • Backed by grocery-pharmacy parent company Hy-Vee

Where it loses points

  • Does not serve every state (for example Mississippi is excluded)
  • Does not publicly name its compounding pharmacy
Signos

Graded #294 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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