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Head-to-head · WeighScore

Premium Health vs Signos

Premium Health
Graded #228

Higher grade

vs+3.6000000000000014
Signos
Graded #293

Lower grade

The verdict

Premium Health takes it — 65/100 to 61.4/100.

Premium Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Premium Health (premiumhealth.us) is a LegitScript-certified telehealth provider offering compounded GLP-1 medications for weight loss via an all-inclusive membership.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePremium Health +7
51
44
Dose & formulationPremium Health +8
72
64
Clinical oversightPremium Health +2
86
84
Labs & monitoringSignos +18
53
71
FulfillmentSignos +2
69
71
Contract termsPremium Health +35
55
20
Premium Health · left barSignos · right bar

The numbers

MetricPremium HealthSignos
WeighScore65/10061.4/100
GradeCC
Scorecard rank#228#293
Semaglutide$275/mo (all doses, compounded)$199/mo (6-month plan, compounded)
Tirzepatide$445/mo (all doses, compounded)$199/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Premium Health

Graded #228 · C

Strengths

  • All-inclusive membership covers medication, supplies, shipping, and provider visits
  • LegitScript certified with verification seal
  • Names three licensed pharmacy partners (Hallandale, Red Rock, Strive)
  • Compounded with Vitamin B12 or B6 to aid tolerance
  • Free consultation and HIPAA-compliant telehealth via Doxy.me

Where it loses points

  • Compounded medications are not FDA-approved
  • Higher base pricing than many compounded competitors ($275/$445)
  • High-dose tiers cost extra ($100-$150/mo)
  • States available not specified on site
  • Cash-pay only; no insurance noted
Signos

Graded #293 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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