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Head-to-head · WeighScore

PCOS Sisters vs TrueMe

PCOS Sisters
Graded #211

Lower grade

vs+1.5999999999999943
TrueMe
Graded #163

Higher grade

The verdict

TrueMe takes it — 67.6/100 to 66/100, but only just.

TrueMe grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. TrueMe is a cash-pay telehealth brand offering compounded semaglutide and tirzepatide with added B vitamins, alongside NAD+, sermorelin and glutathione. PCOS Sisters is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
62
62
Dose & formulationPCOS Sisters +11
88
77
Clinical oversightTrueMe +8
70
78
Labs & monitoringEven
52
52
FulfillmentTrueMe +16
65
81
Contract termsTrueMe +4
41
45
PCOS Sisters · left barTrueMe · right bar

The numbers

MetricPCOS SistersTrueMe
WeighScore66/10067.6/100
GradeCC
Scorecard rank#211#163
Semaglutide$150/mo (plus a separate fee, compounded)$159/mo (compounded)
Tirzepatide$150/mo (plus a separate fee, compounded)$189/mo (compounded)
Coverage12 states6 states
Brand-name accessYesYes
Oral / sublingualYesInjection only
PCOS Sisters

Graded #211 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee
TrueMe

Graded #163 · C

Strengths

  • One price covers consultation, medication, shipping, supplies and provider support, and the site states there are no separate membership fees
  • Same price at every dose, so the cost does not climb as a provider titrates the dose upward
  • Full pricing is published up front — no intake form is required before you can see what you will pay
  • Carries a genuine LegitScript-issued seal (ID 50205625) that resolves on LegitScript's own asset host
  • Names its telehealth platform (Telegra) and physician network (Strive), and the returns address names CarePoint Infusion Pharmacy in Stafford, Texas

Where it loses points

  • Serves only six states (AZ, CO, MO, PA, TX, WI), far narrower coverage than most national GLP-1 telehealth
  • Prices marketed per month are charged every 4 weeks at checkout — 13 charges a year, not 12
  • You pay before completing the medical intake, and approval is not guaranteed at the moment you are charged
  • The 3-month rates ($119 and $139/mo) are a single upfront charge of $357 or $417, not a lower monthly plan
  • A Featured In strip shows CNN, Fox News, Forbes, New York Times and NPR logos with no linked coverage

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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