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Head-to-head · WeighScore

Optimized Health vs Zera Health

Optimized Health
Graded #166

Lower grade

vs+7.599999999999994
Zera Health
Graded #61

Higher grade

The verdict

Zera Health takes it — 74.8/100 to 67.2/100.

Zera Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Zera Health is a telehealth platform for compounded GLP-1 weight loss — semaglutide from $149/mo, tirzepatide from $199/mo, plus oral and low-dose microdose options — prescribed by licensed physicians in…

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Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueZera Health +35
45
80
Dose & formulationEven
75
75
Clinical oversightZera Health +6
76
82
Labs & monitoringOptimized Health +36
89
53
FulfillmentZera Health +25
67
92
Contract termsEven
55
55
Optimized Health · left barZera Health · right bar

The numbers

MetricOptimized HealthZera Health
WeighScore67.2/10074.8/100
GradeCC
Scorecard rank#166#61
Semaglutide$200/mo (starting dose, compounded)$149/mo (compounded)
Tirzepatide$250/mo (starting dose, compounded)$199/mo (compounded)
Coverage5 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesYes
Optimized Health

Graded #166 · C

Strengths

  • Fully transparent pricing published on the website
  • Semaglutide from $200/mo and tirzepatide from $250/mo
  • Lab panels included with clinician-supervised dosing
  • LegitScript certified clinic
  • Lead PA-C with over a decade in obesity medicine

Where it loses points

  • Telehealth limited to MO, IA, KS, UT, and WA
  • Compounded GLP-1 only, not brand-name
  • No insurance billing (cash-pay)
  • PA-led rather than MD/DO-led
Zera Health

Graded #61 · C

Strengths

  • Compounded semaglutide from $149/mo and tirzepatide from $199/mo, plus a $129/mo microdose option
  • Flat pricing — the same monthly cost at every dose as you titrate up
  • All-inclusive: medication, unlimited 24/7 provider messaging, and free shipping bundled in
  • Names its compounding pharmacy — Strive Pharmacy (licensed 503A)
  • Available in all 50 states with same-day approvals

Where it loses points

  • Operates as a technology platform, not the medical provider itself
  • Compounded GLP-1s are not FDA-approved (the site discloses this honestly)
  • Aggressive marketing results claims (e.g. '18% average', '93% kept it off') with 'results not typical' disclaimers
  • Legal entity name not published (footer shows only 'Zera Health')

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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