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Head-to-head · WeighScore

Optimized Health vs SkyRx

Optimized Health
Graded #175

Higher grade

vs+8.300000000000004
SkyRx
Graded #353

Lower grade

The verdict

Optimized Health takes it — 67.2/100 to 58.9/100.

Optimized Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Optimized Health is a concierge medical weight loss and hormone clinic offering clinician-supervised GLP-1 programs with compounded semaglutide and tirzepatide, plus oral options like phentermine.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSkyRx +11
45
56
Dose & formulationOptimized Health +4
75
71
Clinical oversightOptimized Health +8
76
68
Labs & monitoringOptimized Health +37
89
52
FulfillmentOptimized Health +3
67
64
Contract termsOptimized Health +35
55
20
Optimized Health · left barSkyRx · right bar

The numbers

MetricOptimized HealthSkyRx
WeighScore67.2/10058.9/100
GradeCC
Scorecard rank#175#353
Semaglutide$200/mo (starting dose, compounded)$199/mo (all doses, 12-month plan, compounded)
Tirzepatide$250/mo (starting dose, compounded)Not disclosed
Coverage5 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesYes
Optimized Health

Graded #175 · C

Strengths

  • Fully transparent pricing published on the website
  • Semaglutide from $200/mo and tirzepatide from $250/mo
  • Lab panels included with clinician-supervised dosing
  • LegitScript certified clinic
  • Lead PA-C with over a decade in obesity medicine

Where it loses points

  • Telehealth limited to MO, IA, KS, UT, and WA
  • Compounded GLP-1 only, not brand-name
  • No insurance billing (cash-pay)
  • PA-led rather than MD/DO-led
SkyRx

Graded #353 · C

Strengths

  • All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
  • Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
  • Same-day shipping for orders before 2pm ET in temperature-controlled packaging

Where it loses points

  • 199 dollars pricing requires a 12-month subscription paid upfront
  • Tirzepatide only listed as coming soon
  • GLP-1s not yet available in all 50 states; specific states not listed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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