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Head-to-head · WeighScore

Onyx Weight Loss vs yourEra

Onyx Weight Loss
Graded #359

Lower grade

vs+25
yourEra
Graded #13

Higher grade

The verdict

yourEra takes it — 83.8/100 to 58.8/100.

yourEra grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A both-molecule compounded program that publishes its prices up front — semaglutide $199/mo, tirzepatide $299/mo — across a 50-state clinician network, with an optional coaching-plus-labs membership and a NAD+/microdosing menu on the side.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueyourEra +39
43
82
Dose & formulationyourEra +18
64
82
Clinical oversightyourEra +10
75
85
Labs & monitoringyourEra +22
63
85
FulfillmentyourEra +33
53
86
Contract termsyourEra +30
55
85
Onyx Weight Loss · left baryourEra · right bar

The numbers

MetricOnyx Weight LossyourEra
WeighScore58.8/10083.8/100
GradeCB
Scorecard rank#359#13
Semaglutide$228/mo (starting dose, compounded)$199/mo
Tirzepatide$280/mo (starting dose, compounded)$299/mo
Coverage8 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Onyx Weight Loss

Graded #359 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
yourEra

Graded #13 · B

Strengths

  • Transparent, publicly listed pricing — many compounded competitors hide price behind a quiz
  • Both semaglutide and tirzepatide, not a single-drug menu, plus NAD+ and microdosing lines
  • Markets a 50-state licensed-clinician network; no insurance required, HSA/FSA accepted
  • Optional yourEra Optimum membership adds 1:1 coaching, a nutritionist, at-home lab draws and wearables

Where it loses points

  • Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
  • Mid-market pricing ($199 sema / $299 tirz) — above the cheapest compounders
  • No brand-name lane and no oral route — weekly injectable only
  • Thin independent footprint; the 50-state and efficacy claims are self-reported

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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