Head-to-head · WeighScore
Nucore Health vs Vyora Wellness
The verdict
Vyora Wellness takes it — 60.5/100 to 58.6/100, but only just.
Vyora Wellness grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Vyora Wellness offers compounded semaglutide ($299/mo) and compounded tirzepatide ($399/mo) as 4-week subscription plans. Nucore Health is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Nucore Health | Vyora Wellness |
|---|---|---|
| WeighScore | 58.6/100 | 60.5/100 |
| Grade | C | C |
| Scorecard rank | #367 | #322 |
| Semaglutide | $299/mo (starting dose, compounded) | $299/mo (compounded) |
| Tirzepatide | $199/mo (microdose tier, compounded) | $399/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #367 · C
Strengths
- Physician-owned and LegitScript Certified — strong trust signals
- Available nationwide in all 50 states
- Care and pharmacy fulfillment run on OpenLoop Health's licensed network
- Broad menu — compounded GLP-1, microdose tirzepatide, NAD+, sermorelin, MIC B12
Where it loses points
- Published pricing is gated behind the intake quiz — no upfront cost shown
- Legal terms and privacy are posted as downloadable documents, not web pages
- Compounded GLP-1 is not FDA-approved and prescribed off-label (per their own notice)
- Longevity and microdose positioning is marketing; evidence varies by use
Graded #322 · C
Strengths
- LegitScript certified
- Price includes nutritional guidance, 24/7 coaching, and community access
- Both semaglutide and tirzepatide available
- BMI 25+ eligibility threshold (lower than some competitors)
Where it loses points
- State availability not publicly disclosed
- Pricing is above average ($299–$399/mo) compared to competitors
- Compounded only — no brand-name options
- Broader platform (metabolic, longevity, topical products)
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.