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Nucore Health vs Vyora Wellness

By GLP-1 ScorecardUpdated

Nucore Health
Site position #417

Lower grade

Vyora Wellness
Site position #365

Higher grade

Score comparison

Vyora Wellness has the higher recorded score — 60.5/100 to 58.6/100, but only just.

Vyora Wellness grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Vyora Wellness offers compounded semaglutide ($299/mo) and compounded tirzepatide ($399/mo) as 4-week subscription plans. Nucore Health is close behind and may still be the better fit — see the factor split below.

We may earn a commission through these links, at no extra cost to you. Commercial relationships affect placement, but never the WeighScore or our editorial findings. See our disclosure.

Factor by factor

These are recorded editorial marks, not a measure of clinical outcomes. Current prices and terms may differ from those used in the marks. See the methodology.

Cost valueVyora Wellness +6
36
42
Dose & formulationEven
64
64
Clinical oversightNucore Health +3
82
79
Labs & monitoringVyora Wellness +7
53
60
FulfillmentEven
67
67
Contract termsEven
55
55
Nucore Health · top barVyora Wellness · bottom bar

The numbers

Swipe or scroll to compare both providers.

MetricNucore HealthVyora Wellness
WeighScore58.6/10060.5/100
GradeCC
Site position#417#365
Semaglutide$299/mo (starting dose, compounded)$299/mo (compounded)
Tirzepatide$199/mo (microdose tier, compounded)$399/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessNot confirmedNot confirmed
Oral / sublingualNot confirmedNot confirmed
Nucore Health

Site position #417 · C

Strengths

  • Physician-owned and LegitScript Certified — strong trust signals
  • Available nationwide in all 50 states
  • Care and pharmacy fulfillment run on OpenLoop Health's licensed network
  • Broad menu — compounded GLP-1, microdose tirzepatide, NAD+, sermorelin, MIC B12

What to consider

  • Published pricing is gated behind the intake quiz — no upfront cost shown
  • Legal terms and privacy are posted as downloadable documents, not web pages
  • Compounded GLP-1 is not FDA-approved and prescribed off-label (per their own notice)
  • Longevity and microdose positioning is marketing; evidence varies by use
Vyora Wellness

Site position #365 · C

Strengths

  • LegitScript certified
  • Price includes nutritional guidance, 24/7 coaching, and community access
  • Both semaglutide and tirzepatide available
  • BMI 25+ eligibility threshold (lower than some competitors)

What to consider

  • State availability not publicly disclosed
  • Pricing is above average ($299–$399/mo) compared to competitors
  • Compounded only — no brand-name options
  • Broader platform (metabolic, longevity, topical products)

Featured provider

CoreAge Rx

CoreAge Rx scores 89.5/100 (B+). Advertises pricing across doses with no membership fee, but starting-price displays and FAQ payment/refund promises need to be reconciled with the selected plan and refund policy.

Commercial relationships affect this placement. The score comparison above is separate.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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