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Head-to-head · WeighScore

NativeMed vs Signos

NativeMed
Graded #184

Higher grade

vs+5.100000000000001
Signos
Graded #293

Lower grade

The verdict

NativeMed takes it — 66.5/100 to 61.4/100.

NativeMed grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. NativeMed, LLC (nativemed.net) is a Miami, FL-based cash-pay telehealth provider offering compounded semaglutide at promotional $149/mo (regular $299) and compounded tirzepatide at promotional $183/mo…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueNativeMed +30
74
44
Dose & formulationEven
64
64
Clinical oversightSignos +10
74
84
Labs & monitoringSignos +18
53
71
FulfillmentSignos +4
67
71
Contract termsNativeMed +35
55
20
NativeMed · left barSignos · right bar

The numbers

MetricNativeMedSignos
WeighScore66.5/10061.4/100
GradeCC
Scorecard rank#184#293
Semaglutide$149/mo (promotional rate, compounded)$199/mo (6-month plan, compounded)
Tirzepatide$183/mo (promotional rate, compounded)$199/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
NativeMed

Graded #184 · C

Strengths

  • LegitScript Certified (verifiable in the footer)
  • Promotional pricing shown publicly: $149/mo semaglutide, $183/mo tirzepatide
  • Online questionnaire intake, with a live visit added when state law requires it

Where it loses points

  • Pharmacy partners aren't named — described only as 'USA-based' or 'accredited' pharmacies
  • States served aren't listed publicly
  • Prices are promotional — confirm whether they hold past month one or rise to the $299/$399 regular rate
Signos

Graded #293 · C

Strengths

  • Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
  • Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
  • Free rapid shipping; HSA/FSA eligible
  • Real-time glucose insights and app coaching to help sustain results after GLP-1

Where it loses points

  • Compounded GLP-1s are not FDA-approved finished products
  • Headline price is a 6-month-program rate, not month-to-month
  • Only semaglutide is shown in the program; tirzepatide availability is not confirmed
  • Compounding pharmacy partner and state availability are not published on the landing page

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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