Head-to-head · WeighScore
Mixx Health & Wellness vs Signos
The verdict
Mixx Health & Wellness takes it — 62.8/100 to 61.4/100, but only just.
Mixx Health & Wellness grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Mixx Health & Wellness is a telehealth weight-loss platform offering compounded semaglutide and tirzepatide from $120/month with $0 consultations and follow-ups. Signos is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Mixx Health & Wellness | Signos |
|---|---|---|
| WeighScore | 62.8/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #266 | #293 |
| Semaglutide | Not disclosed | $199/mo (6-month plan, compounded) |
| Tirzepatide | Not disclosed | $199/mo (starting dose, compounded) |
| Coverage | 44 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #266 · C
Strengths
- 44 jurisdictions enumerated in the public FAQ — confirm eligibility before intake
- Operating LLC disclosed: Mixx Health and Wellness LLC (Wyoming law)
- Named pharmacy partner: Promise Pharmacy, Palm Harbor FL, (727) 772-0500
- Named founder: Dr. James David Lawrence III, MD, with a public origin story
- $0 consultation fee — free intake and follow-ups
Where it loses points
- Both medications are compounded semaglutide and tirzepatide — not FDA-approved brand drugs
- Dose-tier pricing not available — /pricing and /products pages returned 404
- No LegitScript, PCAB, or BBB trust badges visible
- Wyoming governing-law clause — disputes adjudicated under Wyoming law regardless of your state
- FDA has issued this company a warning letter; the letter is public in FDA's warning-letter database
Graded #293 · C
Strengths
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.